Objectives This study aims to provide an overview of the prevalence, distribution, and
causative agents of fungal keratitis. Methods All the articles with data on the prevalence of …

Polyenes and azoles constitute 2 major drug classes in the antifungal armamentarium used
to treat fungal infections of the eye such as fungal keratitis, endophthalmitis, conjunctivitis …

Itraconazole is a lipophilic drug, which limits its absorption for ocular administration. This
study focused on the incorporation of itraconazole into nanocrystalline carrier system with …

Fungal keratitis is a severe corneal infection that causes irreversible damage to the cornea,
for which conventional drug treatments may be insufficient. With the new generation of drug …

Voriconazole (VCZ) is a broad-spectrum antifungal agent used to treat ocular fungal
keratitis. However, VCZ has low aqueous solubility and chemical instability in aqueous …

Ocular fungal infections can pose severe health conditions that may develop into vision
impairment and blindness. Sertaconazole (STZ) is a widely used antifungal; however, its low …

Mucoadhesive nanoparticles offer prolonged drug residence time at the corneal epithelium
by adhering to the mucous layer of the eye. Here, in this research investigation, voriconazole …

Fungal keratitis (FK) is a devastating ocular disease that can cause corneal opacity and
blindness if not treated effectively. Tolnaftate (TOL) is a selective fungicidal drug against …

Malaria affects more than 200 million people annually around the world, killing a child every
2 min. Artemether (ART) and lumefantrine (LUM) are the gold standard choice to treat …

Abstract Background/Objectives To report the incidence, microbiological profile and in-vitro
antimicrobial susceptibilities of microbial keratitis (MK) in the East of England (EoE) over a 6 …