Inflammation in neurodegenerative diseases–an update
Neurodegeneration, the progressive dysfunction and loss of neurons in the central nervous
system (CNS), is the major cause of cognitive and motor dysfunction. While neuronal …
system (CNS), is the major cause of cognitive and motor dysfunction. While neuronal …
[HTML][HTML] The neural stem cell secretome and its role in brain repair
Compelling evidence from experimental animal disease models and early-phase clinical
trials identifies the transplantation of neural progenitor/stem cells (NSCs) as a viable path …
trials identifies the transplantation of neural progenitor/stem cells (NSCs) as a viable path …
Cellular senescence in progenitor cells contributes to diminished remyelination potential in progressive multiple sclerosis
Cellular senescence is a form of adaptive cellular physiology associated with aging. Cellular
senescence causes a proinflammatory cellular phenotype that impairs tissue regeneration …
senescence causes a proinflammatory cellular phenotype that impairs tissue regeneration …
Hypocretin (orexin) biology and the pathophysiology of narcolepsy with cataplexy
The discovery of hypocretins (orexins) and their causal implication in narcolepsy is the most
important advance in sleep research and sleep medicine since the discovery of rapid eye …
important advance in sleep research and sleep medicine since the discovery of rapid eye …
Neural stem cell transplantation in patients with progressive multiple sclerosis: an open-label, phase 1 study
A Genchi, E Brambilla, F Sangalli, M Radaelli… - Nature medicine, 2023 - nature.com
Innovative pro-regenerative treatment strategies for progressive multiple sclerosis (PMS),
combining neuroprotection and immunomodulation, represent an unmet need. Neural …
combining neuroprotection and immunomodulation, represent an unmet need. Neural …
Three-dimensional hyaluronic acid hydrogel-based models for in vitro human iPSC-derived NPC culture and differentiation
Human induced pluripotent stem cell-derived neural progenitor cells (hiPSC-NPCs) are
considered as a promising cell source for transplantation and have been used for organoid …
considered as a promising cell source for transplantation and have been used for organoid …
[HTML][HTML] Myelin repair in vivo is increased by targeting oligodendrocyte precursor cells with nanoparticles encapsulating leukaemia inhibitory factor (LIF)
Multiple sclerosis (MS) is a progressive demyelinating disease of the central nervous system
(CNS). Many nerve axons are insulated by a myelin sheath and their demyelination not only …
(CNS). Many nerve axons are insulated by a myelin sheath and their demyelination not only …
Neural stem cell transplantation induces stroke recovery by upregulating glutamate transporter GLT-1 in astrocytes
M Bacigaluppi, GL Russo… - Journal of …, 2016 - Soc Neuroscience
Ischemic stroke is the leading cause of disability, but effective therapies are currently widely
lacking. Recovery from stroke is very much dependent on the possibility to develop …
lacking. Recovery from stroke is very much dependent on the possibility to develop …
Stem cell therapy for multiple sclerosis
B Genc, HR Bozan, S Genc, K Genc - Tissue Engineering and …, 2019 - Springer
Multiple sclerosis (MS) is a chronic inflammatory, autoimmune, and neurodegenerative
disease of the central nervous system (CNS). It is characterized by demyelination and …
disease of the central nervous system (CNS). It is characterized by demyelination and …
[HTML][HTML] An overall view of the most common experimental models for multiple sclerosis
S Dedoni, M Scherma, C Camoglio, C Siddi… - Neurobiology of …, 2023 - Elsevier
Multiple sclerosis (MS) is a complex chronic disease with an unknown etiology. It is
considered an inflammatory demyelinating and neurodegenerative disorder of the central …
considered an inflammatory demyelinating and neurodegenerative disorder of the central …