Genotoxic stress impacts pre‐mRNA 3′‐end processing

B Biswas, S Vagner - BioEssays, 2024 - Wiley Online Library
Genotoxic stress, arising from various environmental sources and endogenous cellular
processes, pose a constant threat to genomic stability. Cells have evolved intricate …

[HTML][HTML] Proto-oncogene cSrc-mediated RBM10 phosphorylation arbitrates anti-hypertrophy gene program in the heart and controls cardiac hypertrophy

F Shaji, NK Mohanan, S Shahzad, VP Gowri… - Life Sciences, 2024 - Elsevier
Aims RBM10 is a well-known RNA binding protein that regulates alternative splicing in
various disease states. We have shown a splicing-independent function of RBM10 that …

Star-PAP controls oncogene expression through primary miRNA 3′-end formation to regulate cellular proliferation and tumour formation

NK Mohanan, F Shaji, AP Sudheesh… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Star-PAP is a non-canonical poly (A) polymerase that is down regulated in breast cancer.
While Star-PAP down regulation impairs target mRNA polyadenylation, paradoxically, we …

YTHDC1-Mediated lncRNA MSC-AS1 m6A Modification Potentiates Laryngeal Squamous Cell Carcinoma Development via Repressing ATXN7 Transcription

S Zhang, Q Wu, W Cheng, W Dong, B Kou - Molecular Biotechnology, 2024 - Springer
Laryngeal squamous cell carcinoma (LSCC) has the highest mortality rate among head and
neck squamous cell carcinoma. This study was designed to investigate the biological effect …

Protein-Coupled Phosphoinositide Signaling

T Wen - 2024 - search.proquest.com
Polyphosphoinositide (PIP n) messengers are present in non-membranous regions of
nuclei, where they are assembled into a phosphatidylinositol (PI) 3-kinase (PI3K)/Akt …