[HTML][HTML] Mechanistic role of HPV-associated early proteins in cervical cancer: Molecular pathways and targeted therapeutic strategies

R Bhattacharjee, SS Das, SS Biswal, A Nath… - Critical reviews in …, 2022 - Elsevier
Purpose Cervical cancer (CC), one of the major causes of death of women throughout the
world is primarily caused due to Human Papilloma Virus (HPV) 16 and 18. The early region …

ErbB1-4-dependent EGF/neuregulin signals and their cross talk in the central nervous system: pathological implications in schizophrenia and Parkinson's disease

Y Iwakura, H Nawa - Frontiers in cellular neuroscience, 2013 - frontiersin.org
Ligands for ErbB1-4 receptor tyrosine kinases, such as epidermal growth factor (EGF) and
neuregulins, regulate brain development and function. Thus, abnormalities in their signaling …

Current therapeutic vaccination and immunotherapy strategies for HPV-related diseases

JG Skeate, AW Woodham, MH Einstein… - Human vaccines & …, 2016 - Taylor & Francis
Carcinomas of the anogenital tract, in particular cervical cancer, remains one of the most
common cancers in women, and represent the most frequent gynecological malignancies …

Development of HPV16,18,31,45 E5 and E7 peptides-based vaccines predicted by immunoinformatics tools

A Namvar, HA Panahi, E Agi, A Bolhassani - Biotechnology Letters, 2020 - Springer
Objectives Viral oncoproteins are ideal targets in therapeutic vaccines for functional
inhibition of human papillomaviruses (HPVs). Herein, we designed the peptide constructs …

Therapeutic vaccine strategies against human papillomavirus

H Khallouf, AK Grabowska, AB Riemer - Vaccines, 2014 - mdpi.com
High-risk types of human papillomavirus (HPV) cause over 500,000 cervical, anogenital and
oropharyngeal cancer cases per year. The transforming potential of HPVs is mediated by …

It takes two to tango: a review of oncogenic virus and host microbiome associated Inflammation in head and neck cancer

MG McKeon, JN Gallant, YJ Kim, SR Das - Cancers, 2022 - mdpi.com
Simple Summary Certain viruses, specifically, human papillomavirus (HPV) and Epstein–
Barr virus (EBV), have been linked with the development of head and neck cancer. In this …

MicroRNA-331-3p suppresses cervical cancer cell proliferation and E6/E7 expression by targeting NRP2

T Fujii, K Shimada, A Asano, Y Tatsumi… - International journal of …, 2016 - mdpi.com
Aberrant expression of microRNAs (miRNAs) is involved in the development and
progression of various types of cancers. In this study, we investigated the role of miR-331-3p …

Papillomavirus-associated squamous skin cancers following transplant immunosuppression: one Notch closer to control

K Connolly, P Manders, P Earls, RJ Epstein - Cancer treatment reviews, 2014 - Elsevier
The frequent occurrence of cutaneous squamous cell carcinomas (SCCs) containing weakly
tumorigenic human papillomaviruses (HPVs) following iatrogenic immunosuppression for …

Heterologous prime-boost vaccination using adenovirus and albumin nanoparticles as carriers for human papillomavirus 16 E7 epitope

M Ghanaat, H Kaboosi, B Negahdari… - Current …, 2023 - ingentaconnect.com
Background: Nanocarriers are these days considered an attractive approach in cancer
immunotherapy owing to their ability to deliver antigens to antigen-presenting cells (APCs) …

GW627368X inhibits proliferation and induces apoptosis in cervical cancer by interfering with EP4/EGFR interactive signaling

S Parida, I Pal, A Parekh, B Thakur, R Bharti… - Cell death & …, 2016 - nature.com
PGE2, the major product of cyclooxygenases implicated in carcinogenesis, is significantly
upregulated in cervical cancer. PGE2 via prostanoid receptor EP4 stimulates proliferation …