A considerable number of human diseases have an inflammatory component, and a key
mediator of immune activation and inflammation is inducible nitric oxide synthase (iNOS) …

Free radicals are ubiquitous in our body and are generated by normal physiological
processes, including aerobic metabolism and inflammatory responses, to eliminate invading …

BACKGROUND & AIMS:: The pathogenesis of nonalcoholic steatohepatitis (NASH) remains
poorly understood. Although apoptosis is a common mechanism of liver injury, the extent …

BACKGROUND Nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes (T2D) are
growing public health problems, and are strongly associated. The link between the two …

Chronic infection and inflammation are risk factors for the development of
cholangiocarcinoma, a highly malignant, generally fatal adenocarcinoma originating from …

Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide and
the major risk factors include chronic infections with the hepatitis B (HBV) or C (HCV) virus …

▪ Abstract Inflammation and infection have long been known to downregulate the activity and
expression of cytochrome P450 (CYP) enzymes involved in hepatic drug clearance. This …

Liver damage ranges from acute hepatitis to hepatocellular carcinoma, through apoptosis,
necrosis, inflammation, immune response, fibrosis, ischemia, altered gene expression and …

Nitric oxide (NO) has complex and diverse functions in physiological and pathophysiological
phenomena. The mechanisms of many events induced by NO are now well defined, so that …

With 296 million cases estimated worldwide, chronic hepatitis B virus (HBV) infection is the
most common risk factor for hepatocellular carcinoma (HCC). HBV-encoded oncogene X …