The present report focuses on the various aspects of oral delivery of anticancer drugs. The
significance of oral delivery in cancer therapeutics has been highlighted which principally …

Introduction: Although significant progress has been made in high-throughput screening of
absorption, distribution, metabolism and excretion, and toxicity (ADME-Tox) properties in …

In vitro–in vivo extrapolation (IVIVE) analyses translating high-throughput screening (HTS)
data to human relevance have been limited. This study represents the first report applying …

Epitope-based DNA vaccine development is one application of bioinformatics or in silico
studies, that is, computational methods, including mathematical, chemical, and biological …

Background Physiologically-based population pharmacokinetic modeling (popPBPK)
coupled with in vitro biopharmaceutics tools such as biorelevant dissolution testing can …

Although computational predictions of pharmacokinetics (PK) are desirable at the drug
design stage, existing approaches are often limited by prediction accuracy and human …

Personalized medicine strives to deliver the 'right drug at the right dose'by considering inter-
person variability, one of the causes for therapeutic failure in specialized populations of …

Engineered metal/mineral, lipid and biochemical macromolecule nanomaterials (NMs) have
potential applications in food. Methodologies for the assessment of NM digestion and …

Oral administration of drug products is a strict requirement in many medical indications.
Therefore, bioavailability prediction models are of high importance for prioritization of …

Purpose Oral bioavailability (% F) is a key factor that determines the fate of a new drug in
clinical trials. Traditionally,% F is measured using costly and time-consuming experimental …