Regulation of cholesterol homeostasis in health and diseases: from mechanisms to targeted therapeutics

Y Duan, K Gong, S Xu, F Zhang, X Meng… - Signal Transduction and …, 2022 - nature.com
Disturbed cholesterol homeostasis plays critical roles in the development of multiple
diseases, such as cardiovascular diseases (CVD), neurodegenerative diseases and …

Cholesterol-rich lipid rafts as platforms for SARS-CoV-2 entry

SN Palacios-Rápalo, LA De Jesus-Gonzalez… - Frontiers in …, 2021 - frontiersin.org
Since its appearance, the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2),
the causal agent of Coronavirus Disease 2019 (COVID-19), represents a global problem for …

Statin use in COVID-19 hospitalized patients and outcomes: a retrospective study

H Kouhpeikar, H Khosaravizade Tabasi… - Frontiers in …, 2022 - frontiersin.org
Background Coronavirus disease 2019 (COVID-19) might affect everyone, but people with
comorbidities such as hypertension and cardiovascular disease (CVD) may often have more …

Association of statins for primary prevention of cardiovascular diseases with hospitalization for COVID‐19: A nationwide matched population‐based cohort study

K Bouillon, B Baricault, L Semenzato… - Journal of the …, 2022 - Am Heart Assoc
Background There is little evidence on the relationship between statin use and the risk of
hospitalization attributable to COVID‐19. Methods and Results The French National …

Anti-flavivirus properties of lipid-lowering drugs

CN Farfan-Morales, CD Cordero-Rivera… - Frontiers in …, 2021 - frontiersin.org
Although Flaviviruses such as dengue (DENV) and zika (ZIKV) virus are important human
pathogens, an effective vaccine or antiviral treatment against them is not available. Hence …

The association between the use of statins and clinical outcomes in patients with COVID-19: a systematic review and meta-analysis

CS Kow, SS Hasan - American Journal of Cardiovascular Drugs, 2022 - Springer
Purpose Previously, we have reported potential clinical benefits with the use of statins in
patients with coronavirus disease 2019 (COVID-19) in a meta-analysis, where there was a …

Roles of oxidative injury and nitric oxide system derangements in Kawasaki disease pathogenesis: a systematic review

M Tsuge, K Uda, T Eitoku, N Matsumoto… - International journal of …, 2023 - mdpi.com
Kawasaki disease (KD) is an acute febrile vasculitis that occurs mostly in children younger
than five years. KD involves multiple intricately connected inflammatory reactions activated …

Systematic review and meta-analysis of statin use and mortality, intensive care unit admission and requirement for mechanical ventilation in COVID-19 patients

US Lao, CF Law, DT Baptista-Hon… - Journal of Clinical …, 2022 - mdpi.com
There is mounting evidence that statin use is beneficial for COVID-19 outcomes. We
performed a systematic review and meta-analysis to evaluate the association between statin …

Coronavirus disease-2019 and heart failure: a scientific statement from the Heart Failure Society of America

AS Bhatt, ED Adler, NM Albert… - Journal of cardiac …, 2021 - pmc.ncbi.nlm.nih.gov
The first infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was
reported in December 2019. The ensuing and ongoing pandemic continues to present …

Could statin therapy be useful in patients with coronavirus disease 2019 (COVID-19)?

JD Torres-Peña, N Katsiki… - Frontiers in …, 2021 - frontiersin.org
Acute respiratory distress syndrome (ARDS), resulting from an exaggerated inflammatory
response, is the main cause of death from the coronavirus disease 2019 (COVID-19). Apart …