Emerging droplet microfluidics
Droplet microfluidics generates and manipulates discrete droplets through immiscible
multiphase flows inside microchannels. Due to its remarkable advantages, droplet …
multiphase flows inside microchannels. Due to its remarkable advantages, droplet …
Droplet microfluidics
Droplet-based microfluidic systems have been shown to be compatible with many chemical
and biological reagents and capable of performing a variety of “digital fluidic” operations that …
and biological reagents and capable of performing a variety of “digital fluidic” operations that …
Single-cell analysis and sorting using droplet-based microfluidics
We present a droplet-based microfluidics protocol for high-throughput analysis and sorting
of single cells. Compartmentalization of single cells in droplets enables the analysis of …
of single cells. Compartmentalization of single cells in droplets enables the analysis of …
Microfluidics for cell-based high throughput screening platforms—A review
G Du, Q Fang, JMJ den Toonder - Analytica chimica acta, 2016 - Elsevier
In the last decades, the basic techniques of microfluidics for the study of cells such as cell
culture, cell separation, and cell lysis, have been well developed. Based on cell handling …
culture, cell separation, and cell lysis, have been well developed. Based on cell handling …
High-throughput injection with microfluidics using picoinjectors
Adding reagents to drops is one of the most important functions in droplet-based microfluidic
systems; however, a robust technique to accomplish this does not exist. Here, we introduce …
systems; however, a robust technique to accomplish this does not exist. Here, we introduce …
[HTML][HTML] Overcoming the challenges of membrane protein crystallography
EP Carpenter, K Beis, AD Cameron, S Iwata - Current opinion in structural …, 2008 - Elsevier
Membrane protein structural biology is still a largely unconquered area, given that
approximately 25% of all proteins are membrane proteins and yet less than 150 unique …
approximately 25% of all proteins are membrane proteins and yet less than 150 unique …
Long-range electron tunneling
JR Winkler, HB Gray - Journal of the American Chemical Society, 2014 - ACS Publications
Electrons have so little mass that in less than a second they can tunnel through potential
energy barriers that are several electron-volts high and several nanometers wide. Electron …
energy barriers that are several electron-volts high and several nanometers wide. Electron …
Detecting bacteria and determining their susceptibility to antibiotics by stochastic confinement in nanoliter droplets using plug-based microfluidics
This article describes plug-based microfluidic technology that enables rapid detection and
drug susceptibility screening of bacteria in samples, including complex biological matrices …
drug susceptibility screening of bacteria in samples, including complex biological matrices …
SlipChip
The SlipChip is a microfluidic device designed to perform multiplexed microfluidic reactions
without pumps or valves. The device has two plates in close contact. The bottom plate …
without pumps or valves. The device has two plates in close contact. The bottom plate …
High-throughput single-cell cultivation on microfluidic streak plates
CY Jiang, L Dong, JK Zhao, X Hu, C Shen… - Applied and …, 2016 - Am Soc Microbiol
This paper describes the microfluidic streak plate (MSP), a facile method for high-throughput
microbial cell separation and cultivation in nanoliter sessile droplets. The MSP method …
microbial cell separation and cultivation in nanoliter sessile droplets. The MSP method …