Although the main players of the strigolactone (SL) signaling pathway have been
characterized genetically, how they regulate plant development is still poorly understood. Of …

Heat shock protein 90 (Hsp90) is a highly conserved molecular chaperone that assists in the
maturation of many client proteins involved in cellular signal transduction. As a regulator of …

Aims Hsp90 is regarded as an important therapeutic target in cancer treatment. Client
proteins of Hsp90 like Beclin-1, PI3K, and AKT, are associated with tumor development …

Abstract The Heat Shock Protein 90 (Hsp90) molecular chaperone is a key driver of protein
homeostasis (proteostasis) under physiologically normal and stress conditions. In …

The molecular chaperone Hsp90 (Heat shock protein, 90 kDa) is an abundant and essential
cytosolic protein required for the stability and/or folding of hundreds of client proteins …

Tumors develop in an oxidative environment characterized by peroxynitrite production and
downstream protein tyrosine (Y) nitration. We showed that tyrosine nitration supports …

The skeletal muscle is a highly plastic tissue that shows a remarkable adaptive capacity in
response to acute and resistance exercise, and modifies its composition to adapt to use and …

The chaperonin TRiC/CCT is a large hetero-oligomeric ringed-structure that is essential in
eukaryotes. While present in the nucleus, TRiC/CCT is typically considered to function in the …

Enhanced phenotypic diversity increases a population's likelihood of surviving catastrophic
conditions. Hsp90, an essential molecular chaperone and a central network hub in …