F Fanizza, M Campanile, G Forloni… - Journal of Tissue …, 2022 - journals.sagepub.com
The Organ-on-a-Chip (OoC) technology shows great potential to revolutionize the drugs development pipeline by mimicking the physiological environment and functions of human …
A Bubnys, LH Tsai - Current opinion in neurobiology, 2022 - Elsevier
Alzheimer's disease (AD) is a devastating neurodegenerative disorder affecting the aging population. Despite many studies, there remains an urgent need to identify the root causes …
Self-assembling peptide-based hydrogels have become a highly attractive scaffold for three- dimensional (3D) in vitro disease modeling as they provide a way to create tunable matrices …
Parkinson's disease (PD) and Alzheimer's disease (AD) are neurodegenerative disorders caused by the interaction of genetic, environmental, and familial factors. These diseases …
Alzheimer's disease (AD) is a progressive, neurodegenerative disease that has emerged as a leading risk factor for dementia associated with increasing age. Two‐dimensional (2D) cell …
Neuronal miRNA dysregulation may have a role in the pathophysiology of Alzheimer's disease (AD). miRNA (miR)-124 is largely abundant and a critical player in many neuronal …
The presenilin genes (PSEN1 and PSEN2) are mainly responsible for causing early-onset familial Alzheimer's disease, harboring~ 300 causative mutations, and representing~ 90% of …
L Kumar - Journal of Controlled Release, 2021 - Elsevier
To date, although the microscopic alterations present in Alzheimer's disease (AD) have been well known for over a century only a handful of symptomatic treatments have been …
R Arya, S Jain, S Paliwal, K Madan… - Asian Pacific Journal …, 2024 - journals.lww.com
Alzheimer's disease is a neurological disorder marked by the accumulation of amyloid beta (Aβ) aggregates, resulting from mutations in the amyloid precursor protein. The enzyme β …