Background: Several behaviors, besides psychoactive substance ingestion, produce short-
term reward that may engender persistent behavior, despite knowledge of adverse …

Impulsive people have a strong urge to act without thinking. It is sometimes regarded as a
positive trait but rash impulsiveness is also widely present in clinical disorders such as …

There is a longstanding association between substance-use disorders (SUDs) and the
psychological construct of impulsivity. In the first section of this review, personality and …

There is a high degree of overlap between brain regions involved in processing natural
rewards and drugs of abuse.“Non-drug” or “behavioral” addictions have become …

Adolescence is an evolutionarily conserved developmental phase characterized by
hormonal, physiological, neural and behavioral alterations evident widely across …

Smoking of cigarettes among young adolescents is a pressing public health issue. However,
the neural mechanisms underlying smoking initiation and sustenance during adolescence …

The use of prescription stimulants to enhance healthy cognition has significant social,
ethical, and public health implications. The large number of enhancement users across …

Global treatment of drug addiction costs society billions of dollars annually, but current
psychopharmacological therapies have not been successful at desired rates. The increasing …

Sensation-seeking (SS) is a personality trait that refers to individual differences in motivation
for intense and unusual sensory experiences. It describes a facet of human behaviour that …

The interaction of drugs with biologic targets is a critical area of research, particularly for the
development of medications to treat substance use disorders. In addition to understanding …