Quinoline-containing compounds, such as quinine and chloroquine, have a long-standing
history as potent antimalarial agents. However, the increasing resistance of the Plasmodium …

The application of quinoline-based compounds for the treatment of malaria infections is
hampered by drug resistance. Drug resistance has led to the combination of quinolines with …

(piperazin-1-yl) single bond N-(1H-pyrazolo [3, 4-b] pyridin-3-yl) acetamides are described
as a new class of selective and potent acetylcholinesterase (AChE) inhibitors and amyloid β …

The spreading of new viruses is known to provoke global human health threat. The current
COVID-19 pandemic caused by the recently emerged coronavirus SARS-CoV-2 is one …

Quinoline derivatives are attracting considerable interest due to their biological importance.
In this paper, several 2‐amino‐4‐aryl‐6‐(quinolin‐2‐ylthio) pyridine‐3, 5‐dicarbonitrile …

Malaria is a tropical disease, leading to around half a million deaths annually. Antimalarials
such as quinolines are crucial to fight against malaria, but malaria control is extremely …

In this study, new 7-chloro-4-aminoquinoline-benzimidazole compounds were synthesized
and characterized by NMR, MS, and elemental analysis. These novel hybrids differ in the …

N-Acylhydrazones derived from 7-chloro-4-piperazin-1-yl-quinoline were synthesized and
biologically evaluated for blood-stage of Plasmodium falciparum and Entamoeba histolytica …

Direct Carbamoylation of Quinoline N‐oxides with Hydrazinecarboxamides via C−H Bond
Activation Catalyzed by Copper Catalyst - Li - 2019 - Advanced Synthesis & Catalysis - Wiley …

Chloroquine (CQ) has been the main treatment for malaria in regions where there are no
resistant strains. Molecular hybridization techniques have been used as a tool in the search …