West Africa 2013 Ebola: from virus outbreak to humanitarian crisis

DG Bausch - Marburg-and Ebolaviruses: From Ecosystems to …, 2017 - Springer
The 2013 outbreak of Ebola virus disease (EVD) in West Africa constituted a major
humanitarian crisis. The outbreak numbered over 28,500 cases, more than 10 times the …

Biochemical basis for increased activity of Ebola glycoprotein in the 2013–16 epidemic

MK Wang, SY Lim, SM Lee, JM Cunningham - Cell host & microbe, 2017 - cell.com
Ebola virus (EBOV) infection is characterized by sporadic outbreaks caused by zoonotic
transmission. Fixed changes in amino acid sequence, such as A82V in the EBOV …

A polymorphism within the internal fusion loop of the Ebola virus glycoprotein modulates host cell entry

M Hoffmann, L Crone, E Dietzel, J Paijo… - Journal of …, 2017 - Am Soc Microbiol
The large scale of the Ebola virus disease (EVD) outbreak in West Africa in 2013-2016
raised the question whether the host cell interactions of the responsible Ebola virus (EBOV) …

The glycoproteins of all filovirus species use the same host factors for entry into bat and human cells but entry efficiency is species dependent

M Hoffmann, M González Hernández, E Berger… - PLoS …, 2016 - journals.plos.org
Ebola and marburgviruses, members of the family Filoviridae, can cause severe
hemorrhagic fever in humans. The ongoing Ebola virus (EBOV) disease epidemic in …

Expression of an immunogenic LTB-based chimeric protein targeting Zaire ebolavirus epitopes from GP1 in plant cells

R Ríos-Huerta, E Monreal-Escalante… - Plant cell reports, 2017 - Springer
Key message An antigenic protein targeting two epitopes from the Zaire ebolavirus GP1
protein was expressed in plant cells rendering an antigen capable of inducing humoral …

A comparison of host gene expression signatures associated with infection in vitro by the Makona and Ecran (Mayinga) variants of Ebola virus

A Bosworth, SD Dowall, I Garcia-Dorival, NY Rickett… - Scientific reports, 2017 - nature.com
The Ebola virus (EBOV) variant Makona (which emerged in 2013) was the causative agent
of the largest outbreak of Ebola Virus Disease recorded. Differences in virus-host …

Bombyx mori cell division cycle protein 37 promotes the proliferation of BmNPV

Q Zhang, YF Wu, P Chen, TH Liu, ZQ Dong… - Pesticide Biochemistry …, 2021 - Elsevier
Cell division cycle protein 37 (Cdc37) is a molecular chaperone that actively participates in
many intracellular physiological and biochemical processes as well as pathogen infection …

Response to Comment on “Mutation rate and genotype variation of Ebola virus from Mali case sequences”

T Hoenen, A Groseth, D Safronetz, K Wollenberg… - Science, 2016 - science.org
Rambaut et al. show that the erratum to our report on Ebola virus Makona evolution not only
corrected sample dates modified by others in GenBank but also corrected an additional …

Rhesus macaque IFITM3 gene polymorphisms and SIV infection

M Winkler, S Gärtner, F Wrensch, M Krawczak… - PLoS …, 2017 - journals.plos.org
Interferon-induced transmembrane proteins (IFITMs) have been recognized as important
antiviral effectors of the innate immune system, both in cell culture and in infected humans …

Could bat cell temperature and filovirus filament length explain the emergence of Ebola virus in mammals? Predictions of a thermodynamic model

P Gale - Transboundary and emerging diseases, 2017 - Wiley Online Library
The host reservoir of Zaire ebolavirus (EBOV) remains elusive. One suggestion is that EBOV
emerges in mammals when the precursor virus jumps from mayflies (or other riverine …