Recently, metabolomics analyses have become increasingly common in the general
scientific community as it is applied in several researches relating to diseases diagnosis …

The life sciences are currently being transformed by an unprecedented wave of
developments in molecular analysis, which include important advances in instrumental …

The regenerative potential of mammalian peripheral nervous system neurons after injury is
critically limited by their slow axonal regenerative rate. Regenerative ability is influenced by …

Diabetes is a global health problem caused primarily by the inability of pancreatic β-cells to
secrete adequate levels of insulin. The molecular mechanisms underlying the progressive …

Deubiquitylating enzymes (DUBs) play an essential role in targeted protein degradation and
represent an emerging therapeutic paradigm in cancer. However, their therapeutic potential …

Inter-cellular heterogeneity in metabolic state has been proposed to influence many cancer
phenotypes, including responses to targeted therapy. Here, we track the transitions and …

Metabolomics is now considered a wide-ranging, sensitive and practical approach to
acquire useful information on the composition of a metabolite pool present in any organism …

Pancreatic ductal adenocarcinoma (PDAC) shows great cellular heterogeneity, with
pronounced epithelial and mesenchymal cancer cell populations. However, the cellular …

Metabolomics is playing an increasingly important role in plant science. It aims at the
comprehensive analysis of the plant metabolome which consists both of primary and …

Serine is a vital amino acid in tumorigenesis. While cells can perform de novo serine
synthesis, most transformed cells rely on serine uptake to meet their increased biosynthetic …