α-lipoic acid (ALA, thioctic acid) is an organosulfur component produced from plants,
animals, and humans. It has various properties, among them great antioxidant potential and …

Alpha‐lipoic acid (ALA) is a naturally occurring dithiol micronutrient which acts as a cofactor
for mitochondrial enzyme activity. Due to its potential antioxidant activity, it is considered as …

Diabetic peripheral neuropathy (DPN) is a chronic complication of diabetes mellitus.
Oxidative stress is implicated in DPN progression, suggesting that antioxidant therapy could …

Pyroptosis is primarily considered a pro-inflammatory class of caspase-1-and gasdermin D
(GSDMD)-dependent programmed cell death. Inflammasome activation promotes the …

The occurrence of nonalcoholic fatty liver disease (NAFLD) is associated with type 2
diabetes mellitus (T2DM). The activation of nucleotide‐binding domain and leucine‐rich …

Obesity represents one of the most important challenges in the contemporary world that
must be overcome. Different pathological consequences of these physical conditions have …

Background Oxidative stress underlies metabolic diseases and cognitive impairment; thus,
the use of antioxidants may improve brain function in insulin-resistant conditions. We are the …

The first outbreak of influenza A virus (IAV), which has been circulating for many decades,
has resulted in serious morbidity and mortality. The IAV epidemic has caused serious …

Obesity is a medical term used to describe an over-accumulation of adipose tissue. It causes
abnormal physiological and pathological processes in the body. Obesity is associated with …

Background: Sodium valproate (VPA) is an antiepileptic drug (AED) licensed for epilepsy
and used during pregnancy in various indications. Alpha-lipoic acid (ALA) is a natural …