iPSC preparation and epigenetic memory: does the tissue origin matter?

G Scesa, R Adami, D Bottai - Cells, 2021 - mdpi.com
The production of induced pluripotent stem cells (iPSCs) represent a breakthrough in
regenerative medicine, providing new opportunities for understanding basic molecular …

Erythropoietic properties of human induced pluripotent stem cells‐derived red blood cells in immunodeficient mice

J Deng, M Lancelot, R Jajosky, Q Deng… - American journal of …, 2022 - Wiley Online Library
Transfusion of red blood cells (RBCs) is a life‐saving intervention for anemic patients.
Human induced pluripotent stem cells (iPSC) have the capability to expand and differentiate …

Center-Based iPSC Colony Counting with Multi-Task Learning

MT Sami, D Yan, BR Joy, J Khalil… - … Conference on Data …, 2022 - ieeexplore.ieee.org
iPSCs are pluripotent stem cells generated from adult tissue through a process called
cellular reprogramming. However, cellular reprogramming is a lengthy and inefficient …

[HTML][HTML] Gene Delivery via Octadecylamine-Based Nanoparticles for iPSC Generation from CCD1072-SK Fibroblast Cells

HS Varlı, MA Yıldırım, K Kızılbey… - Current Issues in …, 2024 - pmc.ncbi.nlm.nih.gov
This study presents a novel biotechnological approach using octadecylamine-based solid
lipid nanoparticles (OCTNPs) for the first-time reprogramming of human CCD1072-SK …

[HTML][HTML] Validating human induced pluripotent stem cell-specific quality control tests for the release of an intermediate drug product in a Good Manufacturing Practice …

J Novoa, I Westra, E Steeneveld, NF Neves, L Daleman… - Cytotherapy, 2024 - Elsevier
One of the challenges in Good Manufacturing Practice (GMP)-compliant human induced
pluripotent stem cell (hiPSC) production is the validation of quality control (QC) tests specific …

Attenuating iPSC reprogramming stress with dominant-negative BET peptides

ME Hossain, RR Cevallos, R Zhang, K Hu - Iscience, 2023 - cell.com
Generation of induced pluripotent stem cells (iPSCs) is inefficient and stochastic. The
underlying causes for these deficiencies are elusive. Here, we showed that the …

Open-Vocabulary Scene Graph Generation With Compositional Prompt-Tuning

MT Sami - 2023 - search.proquest.com
Scene graphs are explicit data structures that express the semantics of an image. It is
semantically richer than simple image encodings from Convolutional Neural Networks …

Effect of oocyte factors on epigenetic memory in induced pluripotent stem cells for reduction of cell of origin dependency

A Griffioen - 2024 - studenttheses.uu.nl
The derivation of induced pluripotent stem cells (iPSCs) has opened doors for numerous
applications for which limited human cell sources were available. However, their use has …

Breaking ground to a bioartificial pancreas

AMF Carvalho - 2021 - search.proquest.com
Type 1 diabetes mellitusaffects 45 million people worldwide and its prevalence is rapidly
increasing. This chronic metabolic disease derives from a lack of insulin production by the …