Urine biomarkers in cancer detection: A systematic review of preanalytical parameters and applied methods

S Jordaens, K Zwaenepoel, W Tjalma… - … Journal of Cancer, 2023 - Wiley Online Library
The aim of this review was to explore the status of urine sampling as a liquid biopsy for
noninvasive cancer research by reviewing used preanalytical parameters and protocols. We …

Human papillomavirus: challenges and opportunities for the control of cervical cancer

P Pina-Sanchez - Archives of Medical Research, 2022 - Elsevier
Viruses are the most abundant and genetically diverse entities on the planet, infect all life
forms and have evolved with their hosts. To date, 263 viral species have been identified that …

HPV and DNA methylation testing in urine for cervical intraepithelial neoplasia and cervical cancer detection

R van den Helder, RDM Steenbergen… - Clinical Cancer …, 2022 - AACR
Purpose: Biomarker detection in urine offers a potential solution to increase effectiveness of
cervical cancer screening programs by attracting nonresponders. In this prospective study …

Analytical and clinical performance of extended HPV genotyping with BD Onclarity HPV Assay in home-collected first-void urine: A diagnostic test accuracy study

S Van Keer, A Latsuzbaia, DV Broeck… - Journal of Clinical …, 2022 - Elsevier
Background: Urine collection is a non-invasive self-sampling method offering the prospect of
reaching women un (der)-screened for cervical cancer. The VALHUDES research …

Promise and perils of paper-based point-of-care nucleic acid detection for endemic and pandemic pathogens

N Sritong, MS de Medeiros, LA Basing, JC Linnes - Lab on a Chip, 2023 - pubs.rsc.org
From HIV and influenza to emerging pathogens like COVID-19, each new infectious disease
outbreak has highlighted the need for massively-scalable testing that can be performed …

DNA methylation testing for endometrial cancer detection in urine, cervicovaginal self‐samples and cervical scrapes

BMM Wever, R van den Helder… - … journal of cancer, 2023 - Wiley Online Library
Endometrial cancer incidence is rising and current diagnostics often require invasive biopsy
procedures. DNA methylation marker analysis of minimally‐and non‐invasive sample types …

Triage of human papillomavirus infected women by methylation analysis in first-void urine

S Van Keer, AP van Splunter, J Pattyn, A De Smet… - Scientific reports, 2021 - nature.com
Host cell DNA methylation analysis in urine provides promising triage markers for women
diagnosed with a high-risk (HR) human papillomavirus (HPV) infection. In this study, we …

[HTML][HTML] Experiences and preferences towards collecting a urine and cervicovaginal self-sample among women attending a colposcopy clinic

M Schaafsma, R van den Helder, MCG Bleeker… - Preventive medicine …, 2022 - Elsevier
The effectiveness of cervical cancer screening is hampered by low attendance rates. The
collection of a urine sample is hypothesized to engage non-attenders in cervical cancer …

Extended HPV genotyping to compare HPV type distribution in self-and provider-collected samples for cervical cancer screening

E Rohner, C Edelman, B Sanusi, JW Schmitt… - … Biomarkers & Prevention, 2020 - AACR
Background: Primary high-risk human papillomavirus (hr-HPV) testing of self-collected
cervico-vaginal swabs could increase cervical cancer screening coverage, although triage …

Clinical and analytical evaluation of the RealTime High Risk HPV assay in Colli-Pee collected first-void urine using the VALHUDES protocol

S Van Keer, E Peeters, DV Broeck, P De Sutter… - Gynecologic …, 2021 - Elsevier
Objective Urine self-sampling has gained increasing interest for cervical cancer screening.
In contrast to analytical performance, little information is available regarding the clinical …