Bayesian random-effects meta-analysis using the bayesmeta R package

C Röver - arXiv preprint arXiv:1711.08683, 2017 - arxiv.org
The random-effects or normal-normal hierarchical model is commonly utilized in a wide
range of meta-analysis applications. A Bayesian approach to inference is very attractive in …

Meta‐analysis of few small studies in orphan diseases

T Friede, C Röver, S Wandel… - Research Synthesis …, 2017 - Wiley Online Library
Meta‐analyses in orphan diseases and small populations generally face particular
problems, including small numbers of studies, small study sizes and heterogeneity of results …

Interleukin‐2 receptor antagonists for pediatric liver transplant recipients: a systematic review and meta‐analysis of controlled studies

ND Crins, C Röver, AD Goralczyk… - Pediatric …, 2014 - Wiley Online Library
IL‐2RA are frequently used as induction therapy in liver transplant recipients to decrease the
risk of AR while allowing the reduction of concomitant immunosuppression. The exact …

Management of acute rejection in paediatric liver transplantation

D Thangarajah, M O'Meara, A Dhawan - Pediatric Drugs, 2013 - Springer
The success of paediatric liver transplantation is attributed to improved surgical techniques
and the advent of calcineurin inhibitor-based immunosuppression. Acute rejection (AR) …

Induction treatment with monoclonal antibodies for heart transplantation

JF Delgado, D Vaqueriza, V Sánchez, P Escribano… - Transplantation …, 2011 - Elsevier
Individualization of induction therapy for heart transplantation (HT) is needed, given that only
patients at significant risk for fatal rejection seem to present a favorable risk-benefit ratio. The …

Calcineurin inhibitor sparing in paediatric solid organ transplantation: managing the efficacy/toxicity conundrum

JM Tredger, NW Brown, A Dhawan - Drugs, 2008 - Springer
Despite their efficacy, the calcineurin inhibitors (CNIs) ciclosporin and tacrolimus carry a risk
of debilitating adverse effects, especially nephrotoxicity, that affect the long-term outcome …

Blockade of 4-1BB/4-1BB ligand interactions prevents acute rejection in rat liver transplantation

L Qin, H Guan, X Zhou, J Yin, J Lan… - Chinese medical journal, 2010 - mednexus.org
Background Blocking the 4-1BB/4-1BB ligand (4-1BBL) signal may modulate the secretion
of Th1/Th2 cytokines and prolong the survival of the grafts, which play a key role in organ …

[PDF][PDF] TNF-α 和IL-2 在肝移植急性排斥反应中的表达及意义

樊斌, 李德卫, 冯渊, 杨晓波 - 2011 - zpwz.net
目的检测肿瘤坏死因子α (TnF α) 和白细胞介素2 (IL 2) 在肝移植术后急性排斥反应中的表达
情况, 以评价其作为肝移植术后急性排斥反应早期诊断指标的价值. 方法建立大鼠原位肝移植 …

Optimizing use of basiliximab in liver transplantation

CB Ramirez, A Bozdin, A Frank, W Maley… - … Research and Risk …, 2010 - Taylor & Francis
Antibody induction therapy has not been part of standard immunosuppressive regimens in
liver transplantation. However, in recent years there has been an upward trend in the use of …

[引用][C] CD4^+ 辅助性T 细胞及其细胞因子与肝移植后的免疫

高银杰, 李捍卫, 董宁 - 中国组织工程研究与临床康复, 2009