White adipose tissue is a mesenchymal tissue that begins developing in the fetus.
Classically known for storing the body's fuel reserves, adipose tissue is now recognized as …

Although the regulation of adipose triglyceride lipase and its physiological function remain to
be determined in mouse lines that lack or overexpress the enzyme, present data permit the …

Adiponutrin and a related protein, adipocyte triglyceride lipase (ATGL; also known as
Desnutrin), were recently described as adipocyte-specific proteins with lipid hydrolase …

PNPLA3 (adiponutrin, calcium-independent phospholipase A 2 epsilon [iPLA 2∊]) is an
adipose-enriched, nutritionally regulated protein that belongs to the patatin-like …

Adipose tissue expresses components of the renin-angiotensin system (RAS). Angiotensin
converting enzyme (ACE2), a new component of the RAS, catabolizes the vasoconstrictor …

Background and Aim. Thiazolidinediones (TZDs) can improve hepatic steatosis in
nonalcoholic steatohepatitis (NASH). Angiotensin (Ang) II, the primary effector of renin …

The rising number of obese individuals has become a major burden to the healthcare
systems worldwide. Obesity includes not only the increase of adipose tissue mass but …

Adiponectin is a cytokine hormone originally found to be secreted exclusively by white
adipose tissue. However, recent evidences suggest that adiponectin is also produced in …

BACKGROUND & AIMS: Recent studies have suggested that variations in PNPLA3 are
associated with non-alcoholic fatty liver disease (NAFLD). To gain insight into the potential …

The global burden of metabolic disease demands that we develop new therapeutic
strategies. Many of these approaches may center on manipulating the behavior of …