HMGB1: a common biomarker and potential target for TBI, neuroinflammation, epilepsy, and cognitive dysfunction

YN Paudel, MF Shaikh, A Chakraborti… - Frontiers in …, 2018 - frontiersin.org
High mobility group box protein 1 (HMGB1) is a ubiquitous nuclear protein released by glia
and neurons upon inflammasome activation and activates receptor for advanced glycation …

Effects of common environmental endocrine-disrupting chemicals on zebrafish behavior

Y Tao, Z Li, Y Yang, Y Jiao, J Qu, Y Wang, Y Zhang - Water Research, 2022 - Elsevier
Environmental endocrine-disrupting chemicals (EDCs), a type of exogenous organic
pollutants, are ubiquitous in natural aquatic environments. Therefor, this review focused on …

Role of inflammation in epilepsy and neurobehavioral comorbidities: Implication for therapy

YN Paudel, MF Shaikh, S Shah, Y Kumari… - European journal of …, 2018 - Elsevier
Epilepsy is a devastating condition affecting around 70 million people worldwide. Moreover,
the quality of life of people with epilepsy (PWE) is worsened by a series of comorbidities …

Therapeutic evaluation of solid lipid nanoparticle of quercetin in pentylenetetrazole induced cognitive impairment of zebrafish

N Rishitha, A Muthuraman - Life sciences, 2018 - Elsevier
Background Quercetin is a major flavonoid in various plants. It possesses the multiple
pharmacological actions like vascular integrity and regulatory action of the blood-brain …

Amelioration of cognitive deficit by embelin in a scopolamine-induced Alzheimer's disease-like condition in a rat model

S Bhuvanendran, Y Kumari, I Othman… - Frontiers in …, 2018 - frontiersin.org
Embelin (2, 5-dihydroxy-3-undecyl-1, 4-benzoquinone) is one of the active components
(2.3%) found in Embelia ribes Burm fruits. As determined via in vitro AChE inhibition assay …

[PDF][PDF] Zebrafish as An Emerging Model: An Important Testing Platform for Biomedical Science

A Dubey - Journal of Pharmaceutical Negative Results, 2022 - pnrjournal.com
This is a good thing because animals show other organisms how to stay healthy in their
environment. Biologists can learn more about a lot ofdifferent biological processes by …

Effects of common antiepileptic drugs on teleost fishes

A Salahinejad, D Meuthen, A Attaran… - Science of The Total …, 2023 - Elsevier
Antiepileptic drugs (AEDs) are globally prescribed to treat epilepsy and many other
psychiatric disorders in humans. Their high consumption, low metabolic rate in the human …

Zebrafish as a robust preclinical platform for screening plant-derived drugs with anticonvulsant properties—a review

B Knap, D Nieoczym, U Kundap… - Frontiers in Molecular …, 2023 - frontiersin.org
Traditionally, selected plant sources have been explored for medicines to treat convulsions.
This continues today, especially in countries with low-income rates and poor medical …

Swimming in the maze: An overview of maze apparatuses and protocols to assess zebrafish behavior

R Benvenutti, M Marcon, M Gallas-Lopes… - Neuroscience & …, 2021 - Elsevier
Most preclinical behavioral assays use rodents as model animals, leaving room for species-
specific biases that could be avoided by an expanded cross-species approach. In this …

Zebrafish as an emerging model system in the global south: two decades of research in Brazil

NSS Trigueiro, A Canedo, DLS Braga, AC Luchiari… - Zebrafish, 2020 - liebertpub.com
The zebrafish (Danio rerio) is an emerging model system in several research areas
worldwide, especially in the Global South. In this context, the present study revised the …