Transfer RNAs (tRNA) are best known for their role as adaptors during translation of the
genetic code. Beyond their canonical role during protein biosynthesis, tRNAs also perform …

Covering: up to July 2008 Ribosomally synthesized bacterial natural products rival the
nonribosomal peptides in their structural and functional diversity. The last decade has seen …

Covering: 2000 to up to 2023 α, β-Dehydroamino acids (dhAAs) are unsaturated
nonproteinogenic amino acids found in a wide array of naturally occurring peptidyl …

Cyclodipeptides (CDP) represent a diverse family of small, highly stable, cyclic peptides that
are produced as secondary functional metabolites or side products of protein metabolism by …

Cyclodipeptides and their derivatives belong to the diketopiperazine (DKP) family, which is
comprised of a broad array of natural products that exhibit useful biological properties. In the …

Sirodesmin PL is a phytotoxin produced by the fungus Leptosphaeria maculans, which
causes blackleg disease of canola (Brassica napus). This phytotoxin belongs to the …

Transfer RNA is an essential adapter molecule that is found across all three domains of life.
The primary role of transfer RNA resides in its critical involvement in the accurate translation …

Microorganisms are remarkable chemists, with enzymes as their tools for executing multi-
step syntheses to yield myriad natural products. Microbial synthetic aptitudes are illustrated …

Covering: up to 2012 We review here work on the biosynthesis of diketopiperazines (DKPs),
a large class of natural products with noteworthy biological activities, focusing on the …

In the biosynthesis of the tryptophan‐linked dimeric diketopiperazines (DKPs), cytochromes
P450 selectively couple DKP monomers to generate a variety of intricate and isomeric …