Intrauterine growth restriction and development of the hippocampus: implications for learning and memory in children and adolescents

C Gilchrist, A Cumberland, D Walker… - The Lancet Child & …, 2018 - thelancet.com
Intrauterine growth restriction (IUGR) is often the result of compromised placental function
and suboptimal uteroplacental blood flow. Children born with IUGR have impaired cognitive …

Thyroid hormone analogues: Promising therapeutic avenues to improve the neurodevelopmental outcomes of intrauterine growth restriction

G Chincarini, DW Walker, F Wong… - Journal of …, 2024 - Wiley Online Library
Intrauterine growth restriction (IUGR) is a pregnancy complication impairing fetal growth and
development. The compromised development is often attributed to disruptions of oxygen …

Intrauterine growth restriction causes abnormal embryonic dentate gyrus neurogenesis in mouse offspring that leads to adult learning and memory deficits

AS Brown, M Wieben, S Murdock, J Chang, MLV Dizon… - Eneuro, 2021 - eneuro.org
Human infants who suffer from intrauterine growth restriction (IUGR), which is a failure to
attain their genetically predetermined weight, are at increased risk for postnatal learning and …

Tadalafil treatment in mice for preeclampsia with fetal growth restriction has neuro-benefic effects in offspring through modulating prenatal hypoxic conditions

R Tachibana, T Umekawa, K Yoshikawa, T Owa… - Scientific reports, 2019 - nature.com
We have demonstrated that tadalafil facilitates fetal growth in mice with L-NG-nitroarginine
methyl ester (L-NAME)-induced preeclampsia (PE) with fetal growth restriction (FGR) …

Hippocampal neurogenesis and memory in adolescence following intrauterine growth restriction

CP Gilchrist, AL Cumberland, D Kondos‐Devcic… - …, 2021 - Wiley Online Library
Intrauterine growth restriction (IUGR) is associated with hippocampal alterations that can
increase the risk of short‐term memory impairments later in life. Despite the role of …

[HTML][HTML] Intrauterine growth restriction increases impulsive behavior and is associated with altered dopamine transmission in both medial prefrontal and orbitofrontal …

MB Alves, DP Laureano, R Dalle Molle… - Physiology & …, 2019 - Elsevier
Recent studies have implicated a role for impulsivity in the altered eating behaviors and the
increased risk for obesity consistently associated with intrauterine growth restriction (IUGR) …

SWATH-MS quantitative proteomic investigation of intrauterine growth restriction in a porcine model reveals sex differences in hippocampus development

D Valent, N Yeste, LE Hernández-Castellano… - Journal of …, 2019 - Elsevier
Intrauterine growth restriction (IUGR) is characterized by reduced growth and weight of the
foetus, mainly due to the lack of nutrients and oxygen. Animals affected by IUGR show …

A High-Fat Diet Modifies Brain Neurotransmitter Profile and Hippocampal Proteome and Morphology in an IUGR Pig Model

N Yeste, J Pérez-Valle, A Heras-Molina… - Nutrients, 2022 - mdpi.com
Intrauterine Growth Restriction (IUGR) hinders the correct growth of the fetus during
pregnancy due to the lack of oxygen or nutrients. The developing fetus gives priority to brain …

Diminished insulin sensitivity is associated with altered brain activation to food cues and with risk for obesity–Implications for individuals born small for gestational age

AB Mucellini, PM Miguel, R Dalle Molle, DM Rodrigues… - Appetite, 2022 - Elsevier
While classically linked to memory, the hippocampus is also a feeding behavior modulator
due to its multiple interconnected pathways with other brain regions and expression of …

Hyperthyroidism keeps immunoglobulin levels but reduces milk fat and CD11b/c+ cells on early lactation

MB Sánchez, MCM Lara, FJ Neira… - Molecular and Cellular …, 2024 - Elsevier
Thyroid hormones influence mammary gland differentiation and lactation by binding to
thyroid hormone receptors. Hyperthyroidism disrupts pregnancy and lactation, affecting …