Controversies persist regarding the association between blood pressure (BP) and the risks
of cognitive impairment and dementia due to inconsistent definitions of BP exposure and …

Background—Age-related dementia, most commonly caused by Alzheimer disease or
cerebrovascular factors (vascular dementia), is a major public health threat. Chronic arterial …

Importance The association between late-life blood pressure (BP) and cognition may
depend on the presence and chronicity of past hypertension. Late-life declines in blood …

An estimated 47 million people worldwide are living with dementia in 2015, and this number
is projected to triple by 2050. In the absence of a disease-modifying treatment or cure …

Hypertension is a highly prevalent condition with numerous health risks, and the incidence
of hypertension is greatest among older adults. Traditional discussions of hypertension have …

Hypertension is a highly prevalent condition which has been established as a risk factor for
cardiovascular and cerebrovascular disease. Although the understanding of the relationship …

As the population ages due to demographic trends and gains in life expectancy, the
incidence and prevalence of dementia increases, and the need to understand the etiology …

A systematic review was conducted to identify risk factors associated with the onset and
progression of Alzheimer's disease (AD). Moderate and high quality systematic reviews …

A consensus panel from the United States and Europe was convened recently to update and
revise the 1997 consensus guidelines for the neuropathologic evaluation of Alzheimer's …

Objective Dementia has a multifactorial etiology, but the importance of individual health and
lifestyle related risk factors is often uncertain or based on few studies. The goal of this paper …