Our understanding of depression and its treatment has advanced with the advent of
ketamine as a rapid-acting antidepressant and the development and refinement of tools …

To compare findings across species, neuroscience relies on cross-species homologies,
particularly in terms of brain areas. For cingulate cortex, a structure implicated in behavioural …

With ever-increasing advancements in technology, neuroscientists are able to collect data in
greater volumes and with finer resolution. The bottleneck in understanding how the brain …

Deep brain stimulation (DBS) is an invasive approach to precise modulation of
psychiatrically relevant circuits. Although it has impressive results in open-label psychiatric …

Depression is a mental illness frequently accompanied by disordered energy metabolism. A
dysregulated hypothalamus pituitary adrenal axis response with aberrant glucocorticoids …

Behavioral phenotyping has been gaining prominence due to the increased use of
transgenic animal models of neurological disorders. Repeated testing in the same cohort of …

Major depressive disorder (MDD) and its treatment are challenges for global health.
Optogenetics and chemogenetics are driving MDD research forward by unveiling causal …

Oscillatory brain activities support many physiological functions from motor control to
cognition. Disruptions of the normal oscillatory brain activities are commonly observed in …

The architecture whereby activity across many brain regions integrates to encode individual
appetitive social behavior remains unknown. Here we measure electrical activity from eight …

The perception of control over a stressful experience may determine its impacts and
generate resistance against future stressors. Although the medial prefrontal cortex (PFC) …