Affinity monolith chromatography (AMC) is a liquid chromatographic technique that utilizes a
monolithic support with a biological ligand or related binding agent to isolate, enrich, or …

This article reviews the research contributions along the past five years concerning to
monolithic materials for the development of affinity-based sorbents in the field of …

The use of growth hormone-releasing hormones (GHRHs) is prohibited in sports according
to the regulations of the World Anti-Doping Agency (WADA). The aim of the present study …

Aim: sotatercept is a therapeutic Fc-fusion protein with erythropoiesis-stimulating activity.
Due to a potential abuse of the drug by athletes in professional sports, a sensitive detection …

Over the years, analytical chemistry and immunology have contributed significantly to the
field of clinical diagnosis by introducing quantitative techniques that can detect crucial and …

Introduction: The accurate and comprehensive determination of peptide hormones from
biological fluids has represented a considerable challenge to analytical chemists for …

Therapeutic proteins are a continuously growing class of pharmaceuticals and comprise
several drug candidates with potential performance‐enhancing properties. In particular …

Sotatercept (formerly ACE‐011) is a glycosylated, dimeric fusion protein composed of the
extracellular domain of the human activin receptor type IIA (ActRIIA) and the Fc region of …

This work describes an analytical procedure based on automated affinity purification
followed by liquid chromatography–electrospray tandem mass spectrometry with a …

Purpose Inhibitors of the ActRII signaling pathways represent promising therapeutics for the
treatment of muscular diseases, but also pose risks as performance‐enhancing agents in …