Diabetic cardiomyopathy: current and future therapies. Beyond glycemic control

G Borghetti, D Von Lewinski, DM Eaton… - Frontiers in …, 2018 - frontiersin.org
Diabetes mellitus and the associated complications represent a global burden on human
health and economics. Cardiovascular diseases are the leading cause of death in diabetic …

Anti-inflammatory role of SGLT2 inhibitors as part of their anti-atherosclerotic activity: data from basic science and clinical trials

L Scisciola, V Cataldo, F Taktaz… - Frontiers in …, 2022 - frontiersin.org
Atherosclerosis is a progressive inflammatory disease leading to mortality and morbidity in
the civilized world. Atherosclerosis manifests as an accumulation of plaques in the intimal …

Oral health messiers: diabetes mellitus relevance

R Ahmad, M Haque - Diabetes, Metabolic Syndrome and Obesity, 2021 - Taylor & Francis
This article aims to narrate the various oral complications in individuals suffering from
diabetes mellitus. Google search for “diabetes mellitus and oral complications” was done …

Cardiac resynchronization therapy with a defibrillator (CRTd) in failing heart patients with type 2 diabetes mellitus and treated by glucagon-like peptide 1 receptor …

C Sardu, P Paolisso, C Sacra, M Santamaria… - Cardiovascular …, 2018 - Springer
Objectives To evaluate clinical outcomes in patients with diabetes, treated by cardiac
resynchronization therapy with a defibrillator (CRT-d), and glucagon-like peptide 1 receptor …

Inflammatory related cardiovascular diseases: from molecular mechanisms to therapeutic targets

C Sardu, G Paolisso, R Marfella - Current pharmaceutical …, 2020 - benthamdirect.com
Inflammation is a pathogenic response to multiple factors, that causes over-activation of
different molecules and pro-inflammatory cellular lines. Different behavioral factors and risk …

Protective effect of Galectin-3 inhibitor against cardiac remodelling in an isoprenaline-induced myocardial infarction in type 2 diabetes

MM Mahmoud, MM Hassan, HES Elsayed… - … of Physiology and …, 2024 - Taylor & Francis
Abstract Type 2 Diabetes mellitus (T2DM) has the potential to impair cardiac function and
cause heart failure. We aimed to study the cardioprotective influence of Galactin-3 (Gal-3) …

Type 2 diabetes is independently associated with all-cause mortality secondary to ventricular tachyarrhythmias

K Weidner, M Behnes, T Schupp, J Rusnak… - Cardiovascular …, 2018 - Springer
Objectives The study sought to assess the prognostic impact of type 2 diabetes in patients
presenting with ventricular tachyarrhythmias on admission. Background Data regarding the …

[HTML][HTML] Association between single-point insulin sensitivity estimator and heart failure in older adults: a cross-sectional study

XF Zhu, YT Mo, YQ Hu, YX Feng, EH Liu - Experimental Gerontology, 2024 - Elsevier
Background Heart failure (HF) is a condition caused by a malfunction of the heart's pumping
function. The single-point insulin sensitivity estimator (SPISE) index is a novel indicator for …

Diabetes mellitus and its cardiovascular complications: new insights into an old disease

C Sardu, C De Lucia, M Wallner… - Journal of diabetes …, 2019 - search.proquest.com
In this setting, new drug therapies such as interventional treatments have been developed to
revert these negative conditions in order to ameliorate not only coronary and cardiac …

Metformin restores electrophysiology of small conductance calcium-activated potassium channels in the atrium of GK diabetic rats

X Fu, Y Pan, Q Cao, B Li, S Wang, H Du… - BMC cardiovascular …, 2018 - Springer
Background Small conductance calcium-activated potassium channels (SK channels) play a
critical role in action potential repolarization in cardiomyocytes. Recently, the potential anti …