Gut bacteria modulate the response to immune checkpoint blockade (ICB) treatment in
cancer, but the effect of diet and supplements on this interaction is not well studied. We …

Ample evidence indicates that the gut microbiome is a tumor-extrinsic factor associated with
antitumor response to anti-programmed cell death protein-1 (PD-1) therapy, but …

The tumor microenvironment (TME) influences cancer progression and therapy response.
Therefore, understanding what regulates the TME immune compartment is vital. Here we …

Anti–programmed cell death protein 1 (PD-1) therapy provides long-term clinical benefits to
patients with advanced melanoma. The composition of the gut microbiota correlates with anti …

Cross-talk between the gut microbiota and the host immune system regulates host
metabolism, and its dysregulation can cause metabolic disease. Here, we show that the gut …

Western diet (WD) is one of the major culprits of metabolic disease including type 2 diabetes
(T2D) with gut microbiota playing an important role in modulating effects of the diet. Herein …

Microbiota contribute to the induction of type 2 diabetes by high-fat/high-sugar (HFHS) diet,
but which organs/pathways are impacted by microbiota remain unknown. Using multiorgan …

Interactions between microorganisms and algae during bloom events significantly impacts
their physiology, alters ambient chemistry, and shapes ecosystem diversity. The potential …

Omics technologies enable unbiased investigation of biological systems through massively
parallel sequence acquisition or molecular measurements, bringing the life sciences into the …

Background The gut microbiota contributes to macrophage-mediated inflammation in
adipose tissue with consumption of an obesogenic diet, thus driving the development of …