Cerebral autoregulation monitoring in traumatic brain injury: an overview of recent advances in personalized medicine

FA Zeiler, M Aries, M Czosnyka… - Journal of …, 2022 - liebertpub.com
Impaired cerebral autoregulation (CA) in moderate/severe traumatic brain injury (TBI) has
been identified as a strong associate with poor long-term outcomes, with recent data …

Review of studies on dynamic cerebral autoregulation in the acute phase of stroke and the relationship with clinical outcome

RC Nogueira, M Aries, JS Minhas… - Journal of Cerebral …, 2022 - journals.sagepub.com
Acute stroke is associated with high morbidity and mortality. In the last decades, new
therapies have been investigated with the aim of improving clinical outcomes in the acute …

Targeting autoregulation-guided cerebral perfusion pressure after traumatic brain injury (COGiTATE): a feasibility randomized controlled clinical trial

J Tas, E Beqiri, RC van Kaam, M Czosnyka… - Journal of …, 2021 - liebertpub.com
Managing traumatic brain injury (TBI) patients with a cerebral perfusion pressure (CPP) near
to the cerebral autoregulation (CA)-guided “optimal” CPP (CPPopt) value is associated with …

Cerebrovascular autoregulation monitoring in the management of adult severe traumatic brain injury: a Delphi consensus of clinicians

B Depreitere, G Citerio, M Smith, PD Adelson… - Neurocritical care, 2021 - Springer
Background Several methods have been proposed to measure cerebrovascular
autoregulation (CA) in traumatic brain injury (TBI), but the lack of a gold standard and the …

[HTML][HTML] Continuous cerebrovascular reactivity monitoring in moderate/severe traumatic brain injury: a narrative review of advances in neurocritical care

FA Zeiler, A Ercole, M Czosnyka, P Smielewski… - British journal of …, 2020 - Elsevier
Impaired cerebrovascular reactivity in adult moderate and severe traumatic brain injury (TBI)
is known to be associated with worse global outcome at 6–12 months. As technology has …

Intracranial pressure-derived cerebrovascular reactivity indices and their critical thresholds: A Canadian high resolution-traumatic brain injury validation study

KY Stein, L Froese, M Sekhon, D Griesdale… - Journal of …, 2024 - liebertpub.com
Current neurointensive care guidelines recommend intracranial pressure (ICP) and cerebral
perfusion pressure (CPP) centered management for moderate-severe traumatic brain injury …

Association between cerebrovascular reactivity monitoring and mortality is preserved when adjusting for baseline admission characteristics in adult traumatic brain …

FA Zeiler, A Ercole, E Beqiri, M Cabeleira… - Journal of …, 2020 - liebertpub.com
Cerebral autoregulation, as measured using the pressure reactivity index (PRx), has been
related to global patient outcome in adult patients with traumatic brain injury (TBI). To date …

Temporal dynamics of ICP, CPP, PRx, and CPPopt in high-grade aneurysmal subarachnoid hemorrhage and the relation to clinical outcome

T Svedung Wettervik, T Howells, A Lewén… - Neurocritical care, 2021 - Springer
Background High intracranial pressure (ICP) and low cerebral perfusion pressure (CPP)
may induce secondary brain injury following aneurysmal subarachnoid hemorrhage (aSAH) …

Towards autoregulation-oriented management after traumatic brain injury: increasing the reliability and stability of the CPPopt algorithm

E Beqiri, A Ercole, MJH Aries, MM Placek, J Tas… - Journal of clinical …, 2023 - Springer
Abstract Purpose CPPopt denotes a Cerebral Perfusion Pressure (CPP) value at which the
Pressure-Reactivity index, reflecting the global state of Cerebral Autoregulation, is best …

Deviations from NIRS-derived optimal blood pressure are associated with worse outcomes after pediatric cardiac arrest

MP Kirschen, T Majmudar, F Beaulieu, R Burnett… - Resuscitation, 2021 - Elsevier
Aim Evaluate cerebrovascular autoregulation (CAR) using near-infrared spectroscopy
(NIRS) after pediatric cardiac arrest and determine if deviations from CAR-derived optimal …