Abstract Background The Wnt signaling pathway is a complex network of protein interactions
that functions most commonly in embryonic development and cancer, but is also involved in …

Niclosamide is an oral antihelminthic drug used to treat parasitic infections in millions of
people worldwide. However recent studies have indicated that niclosamide may have broad …

Canonical WNT/β-catenin signaling is involved in most of the mechanisms that lead to the
formation and development of cancer cells. It plays a central role in three cyclic processes …

The plasma protein factor XII (FXII) is the liver-derived zymogen of the serine protease FXIIa
that initiates an array of proteolytic cascades. Zymogen activation, enzymatic FXIIa activity …

Aims Rigosertib (RGS) is a PI3K inhibitor that exerts protective effects against tumor
progression and cancer-related inflammation. This study was aimed to explore the …

Atherosclerosis is the major cause of stroke and heart disease. However, the course and
pathogenesis of atherosclerosis remains unknown. The proliferation and migration of …

Annexin A2 (AnxA2) has been shown to play multiple roles in growth, development, and
metabolism, but the functions of AnxA2 and the signaling pathways associated with AnxA2 …

Polyphosphate (polyP) is a conserved polymer of inorganic phosphate residues that can
reach thousands of moieties in length. PolyP has been implicated in cellular functions …

Activated platelets and mast cells expose the inorganic polymer, polyphosphate (polyP) on
their surfaces. PolyP initiates procoagulant and proinflammatory reactions and the polymer …

The wound healing process is directly related to the type of treatment. Existing methods of
treatment are not responsive enough for severe wounds. The aim of this study was the …