Reprogramming dendritic cells through the immunological synapse: a two‐way street

D Calzada‐Fraile… - European Journal of …, 2023 - Wiley Online Library
Dendritic cells (DCs) bridge innate and adaptive immunity. Their main function is to present
antigens to prime T cells and initiate and shape adaptive responses. Antigen presentation …

Human genetic dissection of papillomavirus-driven diseases: new insight into their pathogenesis

V Béziat - Human genetics, 2020 - Springer
Human papillomaviruses (HPVs) infect mucosal or cutaneous stratified epithelia. There are
5 genera and more than 200 types of HPV, each with a specific tropism and virulence. HPV …

Model membrane systems to reconstitute immune cell signaling

PF Céspedes, D Beckers, ML Dustin… - The FEBS …, 2021 - Wiley Online Library
Understanding the broad variety of functions encoded in cellular membranes requires
experimental systems mimicking both their biochemical composition and biophysical …

Complement-activated interferon-γ–primed human endothelium transpresents interleukin-15 to CD8+ T cells

CB Xie, B Jiang, L Qin, G Tellides… - The Journal of …, 2020 - Am Soc Clin Investig
Alloantibodies in presensitized transplant candidates deposit complement membrane attack
complexes (MACs) on graft endothelial cells (ECs), increasing risk of CD8+ T cell–mediated …

The anti-inflammatory potential of cefazolin as common gamma chain cytokine inhibitor

B Żyżyńska-Granica, B Trzaskowski, M Dutkiewicz… - Scientific Reports, 2020 - nature.com
A continuing quest for specific inhibitors of proinflammatory cytokines brings promise for
effective therapies designed for inflammatory and autoimmune disorders. Cefazolin, a safe …

Tumor necrosis factor receptor superfamily in T cell priming and effector function

J Muller, A Baeyens, ML Dustin - Advances in immunology, 2018 - Elsevier
The tumor necrosis factor receptor superfamily (TNFRSF) and their ligands mediate
lymphoid tissue development and homeostasis in addition to key aspects of innate and …

The abundance and availability of cytokine receptor IL-2Rβ (CD122) constrain the Lymphopenia-Induced homeostatic proliferation of naive CD4 T cells

HR Keller, HK Kim, Y Jo, RE Gress… - The Journal of …, 2020 - journals.aai.org
Lymphopenia-induced homeostatic proliferation (LIP) is a critical mechanism for restoring T
cell immunity upon lymphodepleting insults or infections. LIP is primarily driven by …

[PDF][PDF] Training Year Degree Field Institution

ML Dustin - cicancer.org
2000 NIH HLBP P01 review committee. 2001 NIH ZAI1-NN-IM 1 panel member; NIH NCI
Review of the Experimental Immunology Branch. 2002 NIH P01 phone review. 2003 NIH …