HIV infection continues to be a major global public health issue. The population
heterogeneity in susceptibility or resistance to HIV-1 and progression upon infection is …

Objective: The present study addressed two questions: what fraction of individuals maintain
a sustained high HIV-1 RNA load after the acute HIV-1C infection peak and how long is a …

The first aim of the study is to assess the distribution of HIV-1 RNA levels in subtype C
infection. Among 4,348 drug-naïve HIV-positive individuals participating in clinical studies in …

Background Cluster randomized trials have been utilized to evaluate the effectiveness of
HIV prevention strategies on reducing incidence. Design of such studies must take into …

Background Determining patterns of HIV transmission is increasingly important for the most
efficient use of modern prevention interventions. HIV phylogeny can provide a better …

To address whether sequences of viral gag and env quasispecies collected during the early
post-acute period can be utilized to determine multiplicity of transmitted HIV's, recently …

Background: Most knowledge of primary HIV-1 infection is based on subtype B studies,
whereas the evolution of viral parameters in the early phase of HIV-1 subtype C infection is …

Objectives The aim of this study was to evaluate the HIV‐1 RNA pooled nucleic acid
amplification testing (NAAT) strategy to screen pregnant women in the 'window period'of …

Background HIV-1 nucleotide substitution rates are central for understanding the evolution
of HIV-1. Their accurate estimation is critical for analysis of viral dynamics, identification of …

Abstract Sub-Saharan Africans infected with HIV-1C make up the largest AIDS patient
population in the world and exhibit large heterogeneity in disease progression before …