The cardiovascular response to exercise is largely determined by neurocirculatory control
mechanisms that help to raise blood pressure and modulate vascular resistance which, in …

We conducted a systematic review and meta-analysis to determine the effect of acute
poikilocapnic, high-altitude, and acute isocapnia hypoxemia on muscle sympathetic nerve …

The carotid body (CB) plays a contributory role in the pathogenesis of various respiratory,
cardiovascular, renal, and metabolic diseases through reflex changes in ventilation and …

High-altitude (> 2,500 m) exposure results in increased muscle sympathetic nervous activity
(MSNA) in acclimatizing lowlanders. However, little is known about how altitude affects …

New Findings What is the topic of the review? Sympathoexcitation and sympathetic control
of blood pressure at high altitude. What advances does it highlight? Sustained …

Previous work demonstrates augmented muscle sympathetic nerve activity (MSNA)
responses to the cold pressor test (CPT) in older women. Given its interindividual variability …

With over 14 million people living above 3,500 m, the study of acclimatization and
adaptation to high altitude in human populations is of increasing importance, where …

Sympathetic transduction is reduced following chronic high-altitude (HA) exposure;
however, vascular α-adrenergic signaling, the primary mechanism mediating sympathetic …

Competitive swimmers complete 50‐m front crawl swimming without breathing or with a
limited number of breaths. Breath holding during exercise can trigger diving reflex including …

The presence of bradycardic arrhythmias during volitional apnea at altitude may be caused
by chemoreflex activation/sensitization. We investigated whether bradyarrhythmic episodes …