The mammalian ionotropic glutamate receptor family encodes 18 gene products that
coassemble to form ligand-gated ion channels containing an agonist recognition site, a …

Although glutamate is one of the most important excitatory neurotransmitters of the central
nervous system, its excessive extracellular concentration leads to uncontrolled continuous …

The ionotropic glutamate receptors are ligand-gated ion channels that mediate the vast
majority of excitatory neurotransmission in the brain. The cloning of cDNAs encoding …

Neural stem cells are present both in the developing nervous system and in the adult
nervous system of all mammals, including humans. Little is known, however, about the …

Forty years of research into the function of l-glutamic acid as a neurotransmitter in the
vertebrate central nervous system (CNS) have uncovered a tremendous complexity in the …

NMDA receptor antagonists can induce a schizophrenia-like psychosis, but the role of
NMDA receptors in the pathophysiology of schizophrenia remains unclear. Expression …

Ionotropic glutamate receptors are composed of homomeric or heteromeric configurations of
glutamate receptor subunits. We have cloned a member of a novel class of the rat ionotropic …

The synaptic vesicle protein synaptobrevin (VAMP) has recently been implicated as one of
the key proteins involved in exocytotic membrane fusion. It interacts with the synaptic …

A novel NMDA receptor-like (NMDAR-L) cDNA was isolated that contained an open reading
frame coding for a predicted polypeptide of 1115 amino acids that shares approximately …

The expression of sodium channel α-, β1-and β2-subunit mRNAs was examined in adult rat
DRG neurons in dissociated culture at 1 day in vitro and within sections of intact ganglia by …