What are the functional consequences of neurocognitive deficits in schizophrenia?

MF Green - The American journal of psychiatry, 1996 - europepmc.org
Objective It has been well established that schizophrenic patients have neurocognitive
deficits, but it is not known how these deficits influence the daily lives of patients. The goal of …

Neurocognitive deficits and functional outcome in schizophrenia: are we measuring the “right stuff”?

MF Green, RS Kern, DL Braff, J Mintz - Schizophrenia bulletin, 2000 - academic.oup.com
There has been a surge of interest in the functional consequences of neurocognitive deficits
in schizophrenia. The published literature in this area has doubled in the last few years. In …

The neural basis of human error processing: reinforcement learning, dopamine, and the error-related negativity.

CB Holroyd, MGH Coles - Psychological review, 2002 - psycnet.apa.org
The authors present a unified account of 2 neural systems concerned with the development
and expression of adaptive behaviors: a mesencephalic dopamine system for reinforcement …

A review of MRI findings in schizophrenia

ME Shenton, CC Dickey, M Frumin… - Schizophrenia research, 2001 - Elsevier
After more than 100 years of research, the neuropathology of schizophrenia remains
unknown and this is despite the fact that both: Kraepelin, E., 1919/1971. Dementia praecox …

Context, cortex, and dopamine: a connectionist approach to behavior and biology in schizophrenia.

JD Cohen, D Servan-Schreiber - Psychological review, 1992 - psycnet.apa.org
Connectionist models are used to explore the relationship between cognitive deficits and
biological abnormalities in schizophrenia. Schizophrenic deficits in tasks that tap attention …

Neuropsychological deficits in neuroleptic naive patients with first-episode schizophrenia

AJ Saykin, DL Shtasel, RE Gur, DB Kester… - Archives of general …, 1994 - jamanetwork.com
Background: Medication and chronicity have complicated past attempts to characterize the
neuropsychological performance of patients with schizophrenia. There have been …

Neuropsychological function in schizophrenia: selective impairment in memory and learning

AJ Saykin, RC Gur, RE Gur, PD Mozley… - Archives of general …, 1991 - jamanetwork.com
• Unmedicated schizophrenic patients (according toDSM-III-Rcriteria)(n= 36) and age-
matched normal controls (n= 36), balanced for parental socioeconomic status, were …

Cognitive impairment in schizophrenia

RSE Keefe, PD Harvey - Novel antischizophrenia treatments, 2012 - Springer
Cognitive functioning is moderately to severely impaired in patients with schizophrenia. This
impairment is the prime driver of the significant disabilities in occupational, social, and …

Neuropsychology of first-episode schizophrenia: initial characterization and clinical correlates

RM Bilder, RS Goldman, D Robinson… - American Journal of …, 2000 - Am Psychiatric Assoc
OBJECTIVE: Neuropsychological impairments are well documented in schizophrenia and
are important targets of treatment. Information about the severity and pattern of deficits after …

Auditory working memory and Wisconsin Card Sorting Test performance in schizophrenia

JM Gold, C Carpenter, C Randolph… - Archives of general …, 1997 - jamanetwork.com
Background: Impaired Wisconsin Card Sorting Test (WCST) performance has been one
critical piece of evidence suggesting frontal lobe dysfunction in schizophrenia. However, the …