Exposure routes and health effects of microcystins on animals and humans: A mini-review

IY Massey, F Yang, Z Ding, S Yang, J Guo, M Al-Osman… - Toxicon, 2018 - Elsevier
Microcystins (MCs) pollution has quickly risen in infamy and has become a major problem to
public health worldwide. MCs are a group of monocyclic hepatotoxic peptides, which are …

Grape seed procyanidin extract protects against Pb-induced lung toxicity by activating the AMPK/Nrf2/p62 signaling axis

J Lu, H Jiang, B Liu, R Baiyun, S Li, Y Lv, D Li… - Food and Chemical …, 2018 - Elsevier
Lead (Pb) is one of the most relevant heavy metals contaminants which cause oxidative
stress and threaten human health. The lung is one of the organs most severely damaged by …

Piperine enhances the antioxidant and anti‐inflammatory activities of thymoquinone against microcystin‐LR‐induced hepatotoxicity and neurotoxicity in mice

MM Abdel-Daim, AA Sayed, A Abdeen… - Oxidative Medicine …, 2019 - Wiley Online Library
Microcystin‐(MC‐) LR is the most frequent cyanotoxin produced by Microcystis aeruginosa
cyanobacteria in the contaminated freshwater environment. MC represents a health hazard …

Eugenol attenuates TiO2 nanoparticles-induced oxidative damage, biochemical toxicity and DNA damage in Wistar rats: an in vivo study

MR Wani, N Maheshwari, G Shadab - Environmental Science and …, 2021 - Springer
Abstract Titanium dioxide nanoparticles (TiO 2 NPs) are widely used in food, edible dyes,
and other commercial products. Human exposure to TiO 2 NPs has raised concerns …

Fucoidan alleviates microcystin-LR-induced hepatic, renal, and cardiac oxidative stress and inflammatory injuries in mice

AA AlKahtane, AI Abushouk, ET Mohammed… - … Science and Pollution …, 2020 - Springer
Fucoidans (FUCs) are sulfated polysaccharides that have a wide range of bioactivities. The
current study was designed to evaluate the antioxidant potential of FUC against microcystin …

Spirulina platensis protects against microcystin-LR-induced toxicity in rats

MO Germoush, MMA Fouda, M Kamel… - … Science and Pollution …, 2022 - Springer
Microcystis aeruginosa produces an abundant cyanotoxin (microcystins (MCs) in freshwater
supplies. MCs have adverse health hazards to animals and humans. Microcystin-leucine …

SIRT1‐mediated amelioration of oxidative stress in kidney of alcohol‐aflatoxin‐B1‐induced hepatocellular carcinoma by resveratrol is catalase dependent and GPx …

D Rawat, S Shrivastava, RA Naik… - … of Biochemical and …, 2020 - Wiley Online Library
Hepatocellular carcinoma (HCC) is a type of primary liver cancer and dietary exposure to
aflatoxins is a major risk factor of HCC. The current study aimed to assess the role of …

Dietary Thymoquinone Alone or Combined with Swimming Exercise Protect against Microcystin‐LR‐Induced Oxidative Injury in Mice

AE Altyar, AH Bekhet, M Kamel… - Evidence‐Based …, 2023 - Wiley Online Library
Microcystin‐leucine‐arginine (MCLR) is the most abundant cyanotoxin produced by
cyanobacteria. It induces potent cytotoxicity through oxidative stress and DNA damage …

[HTML][HTML] Ameliorative effect of piracetam on emamectin benzoate induced perturbations in the activity of lactate dehydrogenase in murine system

RA Naik, D Rawat, JD Ahi, RK Koiri - Advances in Redox Research, 2021 - Elsevier
Abstract Emamectin benzoate (4´-deoxy-4´-epimethylaminoavermectin B1) is a macrocyclic
lactone developed for the control of insect pests in edible plant crops. The current study was …

Microcystin-LR promotes necroptosis in primary mouse hepatocytes by overproducing reactive oxygen species

YL Wu, Y He, JJ Shi, TX Zheng, XJ Lin, X Lin - Toxicology and Applied …, 2019 - Elsevier
Abstract Microcystin-LR (MC-LR) is a type of cyclic heptapeptide toxin produced by
cyanobacteria during bloom events. MC-LR-induced cell death is critically involved in its …