Most, if not all mitochondrial functions, including adenosine-5′-triphosphate (ATP)
production and regulation of apoptosis and Ca 2+ homeostasis, are inextricably linked to …

Cerebrovascular diseases such as ischemic stroke, brain hemorrhage, and subarachnoid
hemorrhage provoke cardiac complications such as heart failure, neurogenic stress-related …

In multiple myeloma, an overabundance of monoclonal plasma cells in the bone marrow
induces localized osteolytic lesions that rarely heal due to increased bone resorption and …

Captopril (Cap) as angiotensin-converting enzyme inhibitor (ACEi) is commonly used to
treat hypertension and some types of congestive heart failure. However, few studies …

The Wnt/β-catenin signaling pathway plays a major role in cell survival and proliferation, as
well as in angiogenesis, migration, invasion, metastasis, and stem cell renewal in various …

Programmed cell death eliminates unneeded and dangerous cells in a timely and effective
manner during development. In this review, we examine the role cell death plays during …

Abstract β-catenin is the downstream effector of the Wnt signaling pathway, which regulates
cell proliferation and differentiation. Activation of the Wnt/β‑catenin signaling pathway has …

Canonical Wnt signaling regulates the self-renewal of most if not all stem cell systems. In the
blood system, the role of Wnt signaling has been the subject of much debate but there is …

Apoptosis of alveolar macrophages (AMs) plays a pathogenic role in acute lung injury (ALI)
and its severe type, acute respiratory distress syndrome (ARDS). Mesenchymal stem cells …

Apoptosis of alveolar macrophages following Mycobacterium tuberculosis infection have
been demonstrated to play a central role in the pathogenesis of tuberculosis. In the present …