[HTML][HTML] Angiotensin receptors and neuropathic pain

M Balogh, C Aguilar, NT Nguyen, AJ Shepherd - Pain reports, 2021 - journals.lww.com
Growing evidence implicates the renin–angiotensin system (RAS) in multiple facets of
neuropathic pain (NP). This narrative review focuses primarily on the major bioactive RAS …

Expanding telmisartan's therapeutic horizon: exploring its multifaceted mechanisms beyond cardiovascular disorders

YS Ahire, VA Bairagi, DB Somavanshi… - Future Journal of …, 2024 - Springer
Background Telmisartan, a potent angiotensin II type-1 receptor blocker as well as partial
PPAR–gamma agonist, has emerged as a versatile therapeutic agent with diverse …

In vivo identification of small molecules mediating Gpr126/Adgrg6 signaling during Schwann cell development

EC Bradley, RL Cunningham, C Wilde… - Annals of the New …, 2019 - Wiley Online Library
Abstract Gpr126/Adgrg6, an adhesion family G protein–coupled receptor (aGPCR), is
required for the development of myelinating Schwann cells in the peripheral nervous …

Inhibiting renin angiotensin system in rate limiting step by aliskiren as a new approach for preventing indomethacin induced gastric ulcers

Z Halici, B Polat, E Cadirci, A Topcu, E Karakus… - Chemico-biological …, 2016 - Elsevier
Purpose Previously blocking the renin angiotensin system (RAAS) has been effective in the
prevention of gastric damage. Therefore, the aim of this study was to investigate the effects …

Ramipril Alleviates Oxaliplatin-Induced Acute Pain Syndrome in Mice

H Bouchenaki, A Danigo, A Bernard… - Frontiers in …, 2021 - frontiersin.org
Oxaliplatin is a key drug for colorectal cancer that causes OXP-induced peripheral
neuropathy, a dose-limiting effect characterized by cold and tactile hyperesthesia. The …

[PDF][PDF] Effect of Tarantula cubensis extract (Theranekron) on peripheral nerve healing in an experimental sciatic nerve injury model in rats

Z Kizilay, S Aktas, NK Cetin, MA Kilic… - Turk …, 2019 - turkishneurosurgery.org.tr
ABSTRACT AIM: To investigate the effects of systemic application of Theranekron on
peripheral nerve healing after compression type peripheral nerve injury. MATERIAL and …

Neuroprotective effect of ramipril is mediated by AT2 in a mouse MODEL of paclitaxel-induced peripheral neuropathy

H Bouchenaki, A Bernard, F Bessaguet, S Frachet… - Pharmaceutics, 2022 - mdpi.com
Paclitaxel (PTX)-induced peripheral neuropathy (PIPN) induces numerous symptoms
affecting patient quality of life, leading to decreased doses or even to cessation of anticancer …

Candesartan prevents resiniferatoxin-induced sensory small-fiber neuropathy in mice by promoting angiotensin II-mediated AT2 receptor stimulation

F Bessaguet, A Danigo, L Magy, F Sturtz… - …, 2017 - Elsevier
Sensory defects associated with small-fiber neuropathy (SFN) can lead to profound
disabilities. The relationship between the sensory nervous system and modulation of the …

[HTML][HTML] Effects of Aliskiren, an RAAS inhibitor, on a carrageenan-induced pleurisy model of rats

Y Bayir, H Un, E Cadirci, E Akpinar… - Anais da Academia …, 2018 - SciELO Brasil
Our aim is to investigate the potentially preventive effects of Aliskiren in a carrageenan-
induced lung pleurisy model and to compare the standard anti-inflammatory agents …

The double-edged sword: effects of pregabalin on experimentally induced sciatic nerve transection and crush injury in rats

M Celik, A Kose, D Kose, E Karakus… - International Journal …, 2015 - Taylor & Francis
Aim: The aim of this study was to research the effects of pregabalin on experimentally
induced peripheral nerve crush injuries in rats. Material and method: Forty-two adult female …