Visible-to-NIR-light activated release: from small molecules to nanomaterials

R Weinstain, T Slanina, D Kand, P Klan - Chemical reviews, 2020 - ACS Publications
Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …

Theranostic fluorescent probes

A Sharma, P Verwilst, M Li, D Ma, N Singh… - Chemical …, 2024 - ACS Publications
The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …

Stimulus-cleavable chemistry in the field of controlled drug delivery

Y Xue, H Bai, B Peng, B Fang, J Baell, L Li… - Chemical Society …, 2021 - pubs.rsc.org
Stimulus-cleavable nanoscale drug delivery systems are receiving significant attention
owing to their capability of achieving exquisite control over drug release via the exposure to …

Recent advancements in stimuli responsive drug delivery platforms for active and passive cancer targeting

MA Rahim, N Jan, S Khan, H Shah, A Madni, A Khan… - Cancers, 2021 - mdpi.com
Simple Summary Cancer is one of the leading causes of death globally. Several studies,
efforts and treatment strategies have been put forth for the treatment of different types of …

Conjugates of porphyrinoid-based photosensitizers with cytotoxic drugs: current progress and future directions toward selective photodynamic therapy

VF Otvagin, NS Kuzmina, ES Kudriashova… - Journal of medicinal …, 2022 - ACS Publications
Photodynamic therapy (PDT) is a treatment modality where light-mediated activation of
photosensitizers in a patient's body leads to the generation of cytotoxic reactive oxygen …

Emerging targeted drug delivery strategies toward ovarian cancer

Z Wang, F Meng, Z Zhong - Advanced Drug Delivery Reviews, 2021 - Elsevier
Ovarian cancer is a high-mortality malignancy in women. The contemporary clinical
chemotherapy with classic cytotoxic drugs, targeted molecular inhibitors would mostly fail …

Spatiotemporal control of biology: Synthetic photochemistry toolbox with far-red and near-infrared light

S Jia, EM Sletten - ACS chemical biology, 2021 - ACS Publications
The complex network of naturally occurring biological pathways motivates the development
of new synthetic molecules to perturb and/or detect these processes for fundamental …

Prodrug strategies for targeted therapy triggered by reactive oxygen species

JP Cadahía, V Previtali, NS Troelsen, MH Clausen - MedChemComm, 2019 - pubs.rsc.org
Increased levels of reactive oxygen species (ROS) have been associated with numerous
pathophysiological conditions including cancer and inflammation and the ROS stimulus …

Oxidative‐species‐selective materials for diagnostic and therapeutic applications

C Zhao, J Chen, R Zhong, DS Chen… - Angewandte Chemie …, 2021 - Wiley Online Library
With the increasing recognition of the diverse roles and significance of oxidative species in
the pathogenesis of many diseases, a tremendous amount of work on the development of …

Probing the specific binding of folic acid to folate receptor using amino-functionalized mesoporous silica nanoparticles for differentiation of MCF 7 tumoral cells from …

J Soleymani, M Hasanzadeh, MH Somi… - Biosensors and …, 2018 - Elsevier
Folate receptor (FR) is overexpressed in various cancer cells while its expression in normal
cells is restricted. The present study provides a new folic acid/folate (FA) functionalized …