Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level
F Wang, P Ding, X Liang, X Ding, CB Brandt… - Nature …, 2022 - nature.com
Pigs are valuable large animal models for biomedical and genetic research, but insights into
the tissue-and cell-type-specific transcriptome and heterogeneity remain limited. By …
the tissue-and cell-type-specific transcriptome and heterogeneity remain limited. By …
[HTML][HTML] Pathogen-specific T cells: targeting old enemies and new invaders in transplantation and beyond
A Papadopoulou, M Alvanou, G Karavalakis… - …, 2023 - journals.lww.com
Adoptive immunotherapy with virus-specific cytotoxic T cells (VSTs) has evolved over the
last three decades as a strategy to rapidly restore virus-specific immunity to prevent or treat …
last three decades as a strategy to rapidly restore virus-specific immunity to prevent or treat …
Single-Cell Transcriptomics Reveals Killing Mechanisms of Antitumor Cytotoxic CD4+ TCR-T Cells
Y Liang, Q Xu, S Liu, J Li, F Wang, Z Li, L Liao… - Frontiers in …, 2022 - frontiersin.org
T cell receptor-engineered T cells (TCR-Ts) have emerged as potent cancer
immunotherapies. While most research focused on classical cytotoxic CD8+ T cells, the …
immunotherapies. While most research focused on classical cytotoxic CD8+ T cells, the …
Engineering In Vitro Organ‐Structured Tumor Model for Evaluating Neoantigen‐Specific T Cell Responses in Hepatocellular Carcinoma
Neoantigens derived from somatic mutations in cancer cells can induce antigen‐specific T‐
cell immune response for cancer immunotherapy. However, the 3D models for assessing …
cell immune response for cancer immunotherapy. However, the 3D models for assessing …
Single-cell Approach to Generate Functional TCR-Ts: A Potential Accelerator of TCR-T Cell Therapy for Infectious Diseases
T cell-mediated immune response is essential for host defense against viruses, including the
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which has caused a global …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which has caused a global …