Analogs of microgravity: head-down tilt and water immersion

DE Watenpaugh - Journal of Applied Physiology, 2016 - journals.physiology.org
This article briefly reviews the fidelity of ground-based methods used to simulate human
existence in weightlessness (spaceflight). These methods include horizontal bed rest (BR) …

Blood pressure regulation V: in vivo mechanical properties of precapillary vessels as affected by long-term pressure loading and unloading

O Eiken, IB Mekjavic, R Kölegård - European Journal of Applied …, 2014 - Springer
Recent studies are reviewed, concerning the in vivo wall stiffness of arteries and arterioles in
healthy humans, and how these properties adapt to iterative increments or sustained …

Human cardiovascular adaptation to hypergravity

O Eiken, ME Keramidas… - American Journal of …, 2022 - journals.physiology.org
Despite decades of experience from high-gravitoinertial (G) exposures in aircraft and
centrifuges, information is scarce regarding primary cardiovascular adaptations to+ Gz loads …

Subjective and objective measures of relaxed+ Gz tolerance following repeated+ Gz exposure

JPR Scott, J Jungius, D Connolly… - Aviation, space, and …, 2013 - ingentaconnect.com
Scott JPR, Jungius J, Connolly D, Stevenson AT. Subjective and objective measures of
relaxed+ Gz tolerance following repeated+ Gz exposure. Aviat Space Environ Med 2013; 84 …

External negative pressure transiently reduces intravenous pressure and augments the arteriovenous pressure gradient in the affected limb segment

NA Callender, LØ Høiseth, J Hisdal - PloS one, 2024 - journals.plos.org
Recently intermittent negative pressure has emerged as a potential treatment in vascular
disease and has similarities with established experimental interventions such as lower body …

Circadian rhythm of peripheral perfusion during 10-day hypoxic confinement and bed rest

AC McDonnell, O Eiken, PJ Mekjavic… - European journal of …, 2014 - Springer
Introduction Future planetary habitats will be hypobaric and hypoxic to reduce the risk of
decompression sickness during preparation for extra-vehicular activities. This study was part …

G tolerance vis-à-vis pressure-distension and pressure-flow relationships of leg arteries

O Eiken, I Mekjavic, P Sundblad, R Kölegård - European journal of applied …, 2012 - Springer
During increased gravitoinertial (G) load in the head-to-foot direction, pressures in
dependent vascular beds are commonly raised to levels capable of distending precapillary …

In vivo pressure-flow relation of human cutaneous vessels following prolonged iterative exposures to hypergravity

ME Keramidas, R Kölegård… - American Journal of …, 2023 - journals.physiology.org
The study examined intra-and interlimb variations in cutaneous vessel responsiveness to
acute and repeated transmural pressure elevations. In 11 healthy men, red blood cell flux …

[HTML][HTML] Adaptation to 5 weeks of intermittent local vascular pressure increments; mechanisms to be considered in the development of primary hypertension?

O Eiken, A Elia, H Sköldefors… - American Journal …, 2021 - journals.physiology.org
The aims were to study effects of iterative exposures to moderate elevations of local
intravascular pressure on arterial/arteriolar stiffness and plasma levels of vasoactive …

Increased distensibility in dependent veins following prolonged bedrest

R Kölegård, IB Mekjavic, O Eiken - European journal of applied physiology, 2009 - Springer
Displacement of blood to the lower portion of the body that follows a postural transition from
recumbent to erect is augmented by a prolonged period of recumbency (bedrest) …