Pharmaceutical drugs have become consumer products, with a daily use for some of them.
The volume of production and consumption of drugs is such that they have become …

Sex steroid hormones are synthesized from cholesterol and exert pleiotropic effects notably
in the central nervous system. Pioneering studies from Baulieu and colleagues have …

Zebrafish (Danio rerio) is extensively used in research; however the mechanisms that
control this species sex determination are still poorly understood. In the latest decades, it …

Steroid hormones play essential roles in the reproductive biology of vertebrates. Estrogen
exercises its effect through estrogen receptors and is not only a female reproductive …

Important set of studies have demonstrated the endocrine disrupting activity of Bisphenol A
(BPA). The present work aimed at defining estrogenic-like activity of several BPA structural …

The pituitary gland controls many important physiological processes in vertebrates,
including growth, homeostasis, and reproduction. As in mammals, the teleost pituitary …

The normal brain development and function are delicately driven by an ever-changing
milieu of steroid hormones arising from fetal, placental, and maternal origins. This reliance …

Aim This study evaluated the effect of lead, with or without zinc co-administration, on
steroidogenic and xanthine oxidase (XO)/uric acid (UA)/caspase 3-mediated apoptotic …

Microplastics not only accumulate in the bodies of fishes and cause damage to the organs,
but also cause many other problems, such as reduced reproductive capacity, by acting …

Teleost fish are known to express two isoforms of P450 aromatase, a key enzyme for
estrogen synthesis. One of the isoforms, brain aromatase (AroB), cyp19a1b, is highly …