Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis

S Weibel, G Rücker, LHJ Eberhart… - Cochrane Database …, 2020 - cochranelibrary.com
Background Postoperative nausea and vomiting (PONV) is a common adverse effect of
anaesthesia and surgery. Up to 80% of patients may be affected. These outcomes are a …

Comparison of predictive models for postoperative nausea and vomiting

CC Apfel, P Kranke, LHJ Eberhart… - British journal of …, 2002 - academic.oup.com
Background. In order to identify patients who would benefit from prophylactic amtiemetics,
six predictive models have been described for the risk assessment of postoperative nausea …

[HTML][HTML] A factorial trial of six interventions for the prevention of postoperative nausea and vomiting

CC Apfel, K Korttila, M Abdalla, H Kerger… - New England journal …, 2004 - Mass Medical Soc
Background Untreated, one third of patients who undergo surgery will have postoperative
nausea and vomiting. Although many trials have been conducted, the relative benefits of …

Who is at risk for postdischarge nausea and vomiting after ambulatory surgery?

CC Apfel, BK Philip, OS Cakmakkaya… - Survey of …, 2013 - journals.lww.com
Approximately 1 in 4 patients suffers from postoperative nausea and vomiting. It is fortunate
that risk scores have been developed to help manage this outcome in hospitalized patients …

[HTML][HTML] Nausea and vomiting after surgery under general anesthesia: an evidence-based review concerning risk assessment, prevention, and treatment

D Rüsch, LHJ Eberhart, J Wallenborn… - Deutsches Ärzteblatt …, 2010 - ncbi.nlm.nih.gov
Background The German-language recommendations for the management of postoperative
nausea and vomiting (PONV) have been revised by an expert committee. Major aspects of …

Possibilities and limitations in the pharmacological management of postoperative nausea and vomiting

P Kranke, LHJ Eberhart - European Journal of Anaesthesiology …, 2011 - journals.lww.com
The incidence of postoperative nausea and vomiting (PONV) after a standard anaesthetic
technique consisting of inhalational anaesthetics and opioids and no PONV prophylaxis is …

PONV: a problem of inhalational anaesthesia?

CC Apfel, K Stoecklein, P Lipfert - Best practice & research Clinical …, 2005 - Elsevier
Even nowadays every third or fourth patient suffers from postoperative nausea and vomiting
(PONV) after general anaesthesia with volatile anaesthetics. There is now strong evidence …

Single-dose aprepitant vs ondansetron for the prevention of postoperative nausea and vomiting: a randomized, double-blind Phase III trial in patients undergoing …

P Diemunsch, TJ Gan, BK Philip… - British journal of …, 2007 - academic.oup.com
Background The neurokinin1 antagonist aprepitant is effective for prevention of
chemotherapy-induced nausea and vomiting. We compared aprepitant with ondansetron for …

Update on the management of postoperative nausea and vomiting

AL Kovac - Drugs, 2013 - Springer
New antiemetic drug developments, formulations, guidelines, risk evaluation, and
controversies have occurred in the area of postoperative nausea and vomiting (PONV) …

Development and validation of a postoperative nausea and vomiting intensity scale

R Wengritzky, T Mettho, PS Myles… - British journal of …, 2010 - academic.oup.com
Background Postoperative nausea and vomiting (PONV) is common and of concern to
patients and clinicians. The effect of PONV can range from trivial and transient to major …