Acute-on-chronic liver failure clinical guidelines

JS Bajaj, JG O'Leary, JC Lai, F Wong… - Official journal of the …, 2022 - journals.lww.com
In patients with cirrhosis and chronic liver disease, acute-on-chronic liver failure is emerging
as a major cause of mortality. These guidelines indicate the preferred approach to the …

Hepatorenal syndrome: pathophysiology, diagnosis, and management

DA Simonetto, P Gines, PS Kamath - bmj, 2020 - bmj.com
Hepatorenal syndrome (HRS), the extreme manifestation of renal impairment in patients with
cirrhosis, is characterized by reduction in renal blood flow and glomerular filtration rate …

Terlipressin plus albumin for the treatment of type 1 hepatorenal syndrome

F Wong, SC Pappas, MP Curry… - … England Journal of …, 2021 - Mass Medical Soc
Background The vasoconstrictor terlipressin is used for type 1 hepatorenal syndrome (HRS-
1) in many parts of the world and is part of the clinical practice guidelines in Europe …

News in pathophysiology, definition and classification of hepatorenal syndrome: a step beyond the International Club of Ascites (ICA) consensus document

P Angeli, G Garcia-Tsao, MK Nadim, CR Parikh - Journal of hepatology, 2019 - Elsevier
Renal dysfunction is a common, life-threatening complication occurring in patients with liver
disease. Hepatorenal syndrome (HRS) has been defined as a purely “functional” type of …

[HTML][HTML] Liver—guardian, modifier and target of sepsis

P Strnad, F Tacke, A Koch, C Trautwein - … reviews Gastroenterology & …, 2017 - nature.com
Sepsis and septic shock are characterized by life-threatening organ dysfunction caused by a
dysregulated host response to infection. The liver has a central role during sepsis, and is …

AGA clinical practice update on the evaluation and management of acute kidney injury in patients with cirrhosis: expert review

SL Flamm, F Wong, J Ahn, PS Kamath - Clinical Gastroenterology and …, 2022 - Elsevier
Description The purpose of this American Gastroenterological Association (AGA) Institute
Clinical Practice Update is to review the available published evidence and expert advice …

Acute kidney injury

C Ronco, R Bellomo, JA Kellum - The Lancet, 2019 - thelancet.com
Acute kidney injury (AKI) is defined by a rapid increase in serum creatinine, decrease in
urine output, or both. AKI occurs in approximately 10–15% of patients admitted to hospital …

[HTML][HTML] Urinary NGAL as a diagnostic and prognostic marker for acute kidney injury in cirrhosis: a prospective study

AS Allegretti, XV Parada, P Endres… - Clinical and …, 2021 - journals.lww.com
METHODS: Urinary NGAL was measured in a prospective cohort of 213 US hospitalized
patients with decompensated cirrhosis (161 with AKI and 52 reference patients without AKI) …

AGA clinical practice update on the use of vasoactive drugs and intravenous albumin in cirrhosis: expert review

G Garcia-Tsao, JG Abraldes, NE Rich, VWS Wong - Gastroenterology, 2024 - Elsevier
Description Cirrhosis is a major cause of morbidity and mortality in the United States and
worldwide. It consists of compensated, decompensated, and further decompensated stages; …

Management of hepatorenal syndrome in liver cirrhosis: a recent update

C Bera, F Wong - Therapeutic advances in gastroenterology, 2022 - journals.sagepub.com
Hepatorenal syndrome (HRS) is a serious form of renal dysfunction in patients with cirrhosis
and ascites. It is an important component of the acute-on-chronic liver failure (ACLF) …