Optical microscopy has for centuries been a key tool to study living cells with minimum
invasiveness. The advent of single molecule techniques over the past two decades has …

Quantitative phase imaging (QPI) has emerged as a valuable method for investigating cells
and tissues. QPI operates on unlabelled specimens and, as such, is complementary to …

Background Because of its non-destructive nature, label-free imaging is an important
strategy for studying biological processes. However, routine microscopic techniques like …

Particle tracking is of key importance for quantitative analysis of intracellular dynamic
processes from time-lapse microscopy image data. Because manually detecting and …

We present a combined report on the results of three editions of the Cell Tracking
Challenge, an ongoing initiative aimed at promoting the development and objective …

Label‐free super‐resolution (LFSR) imaging relies on light‐scattering processes in
nanoscale objects without a need for fluorescent (FL) staining required in super‐resolved FL …

摘要针对相衬显微镜采集的细胞图像具有亮度不均衡且细胞与背景对比度较低的问题,
提出一种以U-Net 为基本框架, 结合残差块和注意力机制的细胞分割模型. 首先, 利用具有编码器 …

Infertility affects one in six couples worldwide, and fertility continues to deteriorate globally,
partly owing to a decline in semen quality. Sperm analysis has a central role in diagnosing …

The nucleolus, a recognized biomolecular condensate, serves as the hub for ribosome
biogenesis within the cell nucleus. Its quantity and morphology are discernible indicators of …

Single-cell-resolved systems biology methods, including omics-and imaging-based
measurement modalities, generate a wealth of high-dimensional data characterizing the …