[HTML][HTML] Features of the immunosuppressive tumor microenvironment in endometrial cancer based on molecular subtype
C Zhang, M Wang, Y Wu - Frontiers in Oncology, 2023 - frontiersin.org
Endometrial cancer (EC) is one of the three most prevalent gynecological tumors affecting
women and is the most prevalent gynecological malignancy in the developed world. Its …
women and is the most prevalent gynecological malignancy in the developed world. Its …
Neoadjuvant chemoimmunotherapy increases tumor immune lymphocytes infiltration in resectable non-small cell lung cancer
T Chen, Z Cao, Y Sun, J Huang, S Shen, Y Jin… - Annals of Surgical …, 2023 - Springer
Background Neoadjuvant chemoimmunotherapy treatment (NCIT) has achieved great
success for non-small cell lung cancer (NSCLC); however, the intrinsic mechanism …
success for non-small cell lung cancer (NSCLC); however, the intrinsic mechanism …
[HTML][HTML] Body mass index and adiposity influence responses to immune checkpoint inhibition in endometrial cancer
N Gómez-Banoy, EJ Ortiz, CS Jiang… - The Journal of …, 2024 - Am Soc Clin Investig
BACKGROUND. Obesity is the foremost risk factor in the development of endometrial cancer
(EC). However, the impact of obesity on the response to immune checkpoint inhibitors (ICI) …
(EC). However, the impact of obesity on the response to immune checkpoint inhibitors (ICI) …
[HTML][HTML] High DNA methylation age deceleration defines an aggressive phenotype with immunoexclusion environments in endometrial carcinoma
J Hao, T Liu, Y Xiu, H Yuan, D Xu - Frontiers in Immunology, 2023 - frontiersin.org
Like telomere shortening, global DNA hypomethylation occurs progressively with cellular
divisions or in vivo aging and functions as a mitotic clock to restrain malignant …
divisions or in vivo aging and functions as a mitotic clock to restrain malignant …
[HTML][HTML] Prognosis of polymerase epsilon (POLE) mutation in high-grade endometrioid endometrial cancer: Systematic review and meta-analysis
J Casanova, GS Duarte, AG da Costa, A Catarino… - Gynecologic …, 2024 - Elsevier
Background POLE mutated endometrial carcinomas may represent a subspecific type of
tumors harboring a more favorable prognosis. Grade 3 (G3 or high-grade) endometrioid …
tumors harboring a more favorable prognosis. Grade 3 (G3 or high-grade) endometrioid …
[HTML][HTML] Prediction of Prognosis, Immunotherapy and Chemotherapy with an Immune-Related Risk Score Model for Endometrial Cancer
W Wei, B Ye, Z Huang, X Mu, J Qiao, P Zhao, Y Jiang… - Cancers, 2023 - mdpi.com
Simple Summary Endometrial cancer (EC) is one of the most common gynecologic cancers.
However, its clinical therapy remains unsatisfying due to the lack of effective treatment …
However, its clinical therapy remains unsatisfying due to the lack of effective treatment …
Downregulation of ATP5F1D inhibits mtROS/NLRP3/caspase-1/GSDMD axis to suppress pyroptosis-mediated malignant progression of endometrial cancer
Y Cheng, X Chen, D Hu, J Du, Y Xing, X Liang… - International …, 2024 - Elsevier
Purpose In developed countries, endometrial cancer (EC) is the most prevalent
gynecological cancer and its occurrence is associated with chronic inflammation. ATP5F1D …
gynecological cancer and its occurrence is associated with chronic inflammation. ATP5F1D …
[HTML][HTML] Re-stratification of patients with copy-number low endometrial cancer by clinicopathological characteristics
L Liwei, L He, D Yibo, Z Luyang, S Zhihui… - World Journal of …, 2023 - Springer
Objective To stratify patients with copy-number low (CNL) endometrial cancer (EC) by
clinicopathological characteristics. Methods EC patients who underwent surgery between …
clinicopathological characteristics. Methods EC patients who underwent surgery between …
Identification of an immune-related metabolic gene signature to predict possible prognosis in endometrial cancer and reveals immune landscape feature
Y Cheng, P Yu, X Liang, Y Yang - 2023 - ejgo.net
The immunotherapy of endometrial cancer (EC) has gradually attracted attention and
metabolic reprogramming is associate with tumor immune infiltration. Our goal was to use …
metabolic reprogramming is associate with tumor immune infiltration. Our goal was to use …