Epidemiological studies established that elevated homocysteine, an important intermediate
in folate, vitamin B12, and one carbon metabolism, is associated with poor health, including …

Homocysteine, a non-protein amino acid, is an important risk factor for ischemic heart
disease and stroke in humans. This review provides an overview of homocysteine influence …

Elevated level of the nonprotein amino acid homocysteine (Hcy) is a risk factor for
cardiovascular diseases, neurodegenerative diseases, and neural tube defects. However, it …

Numerous epidemiological studies have demonstrated that hyperhomocysteinemia (HHcy)
is a strong and independent risk factor for cardiovascular disease. HHcy can result from a …

This review covers briefly the major conditions, genetic and non‐genetic, sometimes leading
to abnormally elevated methionine, with emphasis on recent developments. A major aim is …

High density lipoproteins (HDL) are susceptible to structural modifications mediated by
various mechanisms including oxidation, glycation, homocysteinylation or enzymatic …

The first edition of this book, Chemical Warfare Agents: Toxicity at Low Levels, was
published just prior to the terrorist attacks of September 11th, 2001. Reflecting a greater …

Accumulating evidence suggests that homocysteine (Hcy) metabolite, the thioester Hcy-
thiolactone, plays an important role in atherothrombosis. Hcy-thiolactone is a product of an …

Homocysteine is thought to be a non-protein amino acid. However, in vitro studies suggest
that homocysteine is likely to be incorporated by indirect mechanisms into proteins in living …

Several polymorphisms of genes involved in one‐carbon metabolism have been identified.
The reported metabolic phenotypes are often based on small studies providing inconsistent …