2.1 Introduction The healthy human pancreas adopts exocrine secretion to nutrient ingestion
and there are numerous studies investigating pancreatic exocrine response to various …

The pathogenesis of acute pancreatitis is poorly understood, despite well-recognised
precipitating factors. Current evidence suggests that the earliest abnormalities of acute …

Background: Although the incidence of acute pancreatitis (AP) in children is increasing,
management recommendations rely on adult published guidelines. Pediatric-specific …

BACKGROUND After 50 yr in which nasoenteric feeding was considered contraindicated in
acute pancreatitis (AP), several clinical studies have shown that early nasojejunal (NJ) …

Chronic pancreatitis is a disease of the pancreas in which recurrent inflammatory episodes
result in replacement of pancreatic parenchyma by fibrous connective tissue. This fibrotic …

Oxidative stress may be an important determinant of the severity of acute pancreatitis. One-
electron reduction of oxidants generates reactive oxygen species (ROS) via redox cycling …

BACKGROUND & AIMS: In acute pancreatitis, traditional treatment has been initial fasting
on purpose to avoid activation of proteolytic enzymes and pancreatic enzyme secretion. The …

OBJECTIVES: The aims of this study were to define the indications for, and to evaluate the
cost-effectiveness of, nutritional support in patients with acute pancreatitis. METHODS: All …

BACKGROUND The pharmacological inhibition of exocrine pancreatic secretion with the
somatostatin analogue octreotide has been advocated as a specific treatment of acute …

Objective: To compare the efficacy and safety of early, nasogastric enteral nutrition (EN) with
total parenteral nutrition (TPN) in patients with predicted severe acute pancreatitis (SAP) …