Biomimetic hydrogels with spatial-and temporal-controlled chemical cues for tissue engineering
Biomimetic hydrogels have emerged as the most useful tissue engineering scaffold
materials. Their versatile chemistry can recapitulate multiple physical and chemical features …
materials. Their versatile chemistry can recapitulate multiple physical and chemical features …
Mimicking the Brain Extracellular Matrix in Vitro: A Review of Current Methodologies and Challenges
The brain's extracellular matrix (ECM), a 3‐dimensional macromolecular network that
supports cell growth and viability, has crucial roles in homeostasis and disease. Accurate …
supports cell growth and viability, has crucial roles in homeostasis and disease. Accurate …
Three-dimensional brain-like microenvironments facilitate the direct reprogramming of fibroblasts into therapeutic neurons
Biophysical cues can improve the direct reprogramming of fibroblasts into neurons that can
be used for therapeutic purposes. However, the effects of a three-dimensional (3D) …
be used for therapeutic purposes. However, the effects of a three-dimensional (3D) …
Engineering spheroids potentiating cell-cell and cell-ECM interactions by self-assembly of stem cell microlayer
Numerous methods have been reported for the fabrication of 3D multi-cellular spheroids and
their use in stem cell culture. Current methods typically relying on the self-assembly of …
their use in stem cell culture. Current methods typically relying on the self-assembly of …
DAP5 drives translation of specific mRNA targets with upstream ORFs in human embryonic stem cells
Death associated protein 5 (DAP5/eIF4G2/NAT1) is a member of the eIF4G translation
initiation factors that has been shown to mediate noncanonical and/or cap-independent …
initiation factors that has been shown to mediate noncanonical and/or cap-independent …
Ligand functionalization of titanium nanopattern enables the analysis of cell–ligand interactions by super-resolution microscopy
The spatiotemporal aspects of early signaling events during interactions between cells and
their environment dictate multiple downstream outcomes. While advances in nanopatterning …
their environment dictate multiple downstream outcomes. While advances in nanopatterning …
The cancer cell adhesion resistome: mechanisms, targeting and translational approaches
E Dickreuter, N Cordes - Biological chemistry, 2017 - degruyter.com
Cell adhesion-mediated resistance limits the success of cancer therapies and is a great
obstacle to overcome in the clinic. Since the 1990s, where it became clear that adhesion of …
obstacle to overcome in the clinic. Since the 1990s, where it became clear that adhesion of …
Head-to-head comparison of two engineered cardiac grafts for myocardial repair: from scaffold characterization to pre-clinical testing
Cardiac tissue engineering, which combines cells and supportive scaffolds, is an emerging
treatment for restoring cardiac function after myocardial infarction (MI), although, the optimal …
treatment for restoring cardiac function after myocardial infarction (MI), although, the optimal …
Generation, transmission, and regulation of mechanical forces in embryonic morphogenesis
Embryonic morphogenesis is a biological process which depicts shape forming of tissues
and organs during development. Unveiling the roles of mechanical forces generated …
and organs during development. Unveiling the roles of mechanical forces generated …
Discovery and characterization of a potent and specific peptide ligand targeting endothelial progenitor cells and endothelial cells for tissue regeneration
Endothelial progenitor cells (EPCs) and endothelial cells (ECs) play a vital role in
endothelialization and vascularization for tissue regeneration. Various EPC/EC targeting …
endothelialization and vascularization for tissue regeneration. Various EPC/EC targeting …