[HTML][HTML] Skeletal muscle aging: influence of oxidative stress and physical exercise

MJ Gomes, PF Martinez, LU Pagan, RL Damatto… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Skeletal muscle abnormalities are responsible for significant disability in the elderly.
Sarcopenia is the main alteration occurring during senescence and a key public health …

Activins and inhibins: roles in development, physiology, and disease

M Namwanje, CW Brown - Cold Spring Harbor …, 2016 - cshperspectives.cshlp.org
Since their original discovery as regulators of follicle-stimulating hormone (FSH) secretion
and erythropoiesis, the TGF-β family members activin and inhibin have been shown to …

Diagnosis and antenatal management of congenital cytomegalovirus infection

BL Hughes, C Gyamfi-Bannerman… - American journal of …, 2016 - Elsevier
Congenital cytomegalovirus (CMV) is the most common viral infection, affecting nearly
40,000 infants each year in the United States. Of seronegative women, 1-4% will acquire a …

Mitochondrial dysfunction and skeletal muscle atrophy: Causes, mechanisms, and treatment strategies

GB Kubat, E Bouhamida, O Ulger, I Turkel, G Pedriali… - Mitochondrion, 2023 - Elsevier
Skeletal muscle, which accounts for approximately 40% of total body weight, is one of the
most dynamic and plastic tissues in the human body and plays a vital role in movement …

Inhibin at 90: from discovery to clinical application, a historical review

Y Makanji, J Zhu, R Mishra, C Holmquist… - Endocrine …, 2014 - academic.oup.com
When it was initially discovered in 1923, inhibin was characterized as a hypophysiotropic
hormone that acts on pituitary cells to regulate pituitary hormone secretion. Ninety years …

Mood disorders in the elderly: prevalence, functional impact, and management challenges

LCL Valiengo, F Stella, OV Forlenza - … disease and treatment, 2016 - Taylor & Francis
Despite the lower prevalence of severe mood disorders in the elderly as compared to
younger adults, late-life depression and bipolar disorder (BD) are more strongly associated …

Exercise training improves the IL-10/TNF-α cytokine balance in the gastrocnemius of rats with heart failure

L Calegari, RB Nunes, BB Mozzaquattro… - Brazilian journal of …, 2018 - Elsevier
Objective This study examined the effects of exercise training (ExT) upon concentration of
tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6) and interleukin-10 (IL-10) in the …

Myostatin from the heart: local and systemic actions in cardiac failure and muscle wasting

A Breitbart, M Auger-Messier… - American Journal of …, 2011 - journals.physiology.org
A significant proportion of heart failure patients develop skeletal muscle wasting and cardiac
cachexia, which is associated with a very poor prognosis. Recently, myostatin, a cytokine …

[HTML][HTML] Cardiac cachexia: perspectives for prevention and treatment

MP Okoshi, RV Capalbo, FG Romeiro… - Arquivos brasileiros de …, 2016 - SciELO Brasil
Cachexia is a prevalent pathological condition associated with chronic heart failure. Its
occurrence predicts increased morbidity and mortality independent of important clinical …

[HTML][HTML] Long-term low intensity physical exercise attenuates heart failure development in aging spontaneously hypertensive rats

LU Pagan, RL Damatto, MDM Cezar… - Cellular physiology and …, 2015 - karger.com
Background: Physical exercise is a strategy to control hypertension and attenuate pressure
overload-induced cardiac remodeling. The influence of exercise on cardiac remodeling …