The inherent biology of neural stem cells (NSCs) endows them with capabilities that not only
circumvent many of the limitations of other gene transfer vehicles, but that enable a variety of …

Spontaneous neural tissue repair occurs in patients affected by inflammatory and
degenerative disorders of the central nervous system (CNS). However, this process is not …

Endocannabinoids are neuromodulators that act as retrograde synaptic messengers
inhibiting the release of different neurotransmitters in cerebral areas such as hippocampus …

Besides their capacity to give rise to neurons and/or glia, neural stem cells (NSCs) appear to
inherently secrete neurotrophic factors beneficial to injured neurons. To test this potential …

Many central nervous system regions at all stages of life contain neural stem cells (NSCs).
We explored how these disparate NSC pools might emerge. A traceable clone of human …

Here we examined the ability of human neural progenitors from the embryonic forebrain,
expanded for up to a year in culture in the presence of growth factors, to respond to …

The capability for in vitro expansion of human neural stem cells (HNSCs) provides a well
characterized and unlimited source alternative to using primary fetal tissue for neuronal …

Object. Cultures containing human neural stem and progenitor cells (neurospheres) have
the capacity to proliferate and differentiate into the major phenotypes of the adult brain …

We have examined long-term growth-factor expanded human neural progenitors following
transplantation into the adult rat brain. Cells, obtained from the forebrain of a 9-week old …

Transplantation of genetically engineered cells into the CNS offers immense potential for the
treatment of several neurological disorders. Monitoring expression levels of transgenes and …